The Application Of Emission Computerized Tomography In The Rebuilding And Reconstruction Of Jaw Defects With Scaffolds Materials Of Bone Tissue Engineering

Objectives: In recent years, the application of scaffold materials of bone tissueengineering to repair and reconstruct bone defects has become the most important studydirection in the field of bone tissue engineering, and how to monitor effectively theosteogenic activity of scaffolds and the progress of vascularization has been one of themost important research. In this study, single photon emission computed tomographytechnique (SPECT) has been used to monitor regularly jaw defect repairing with thetissue engineered bone in order to seek a suitable method for researching theosteogenesis characteristic of the scaffolds, and to prove it has a good prospect inclinical application.Methods: to select clinical cases reasonablely, to improve the postoperative follow-upwork after related surgery, and to examine regularly with SPECT. The radionuclide boneimaging pictures were analyzed qualitatively and quantitatively by related software.Results: It could be clearly judged according to the ECT images acquired by regularfollow-up that the tracer in operation area had a greater concentration than that in thecontrol side, and the operation area with tracer concentration manifested as darkcoloring. The qualitative analysis explained osteogenic activity and vascularregeneration of the scaffold material in the repairing of jaw defect. SPECT software wasused for the quantitative analysis of the radiation counting in the interesting region ofthe image, and the conclusion was the same. In addition, monitoring sensitivity and persistence could be seen as the extension of time axis.Conclusions: scaffolds materials of bone tissue engineering used in repairing bonedefects can promote and improve its osteogenic characteristics effectively, and has acertain advantage on osteogenic differentiation and vascular regeneration that itimproves the repairing and reconstruction of bone defect effectively. It is a greatpotential scaffold material of bone tissue engineering. It is very important to applyradionuclide bone imaging technique to monitor jaw defect repairing by InorganicElements Scaffold material. Radionuclide bone imaging technique, which hascharacteristics of sensitive, intuitive, accurate and enduring, has become a main indexon the clinical dynamic monitoring of bone regeneration in the jaw defect repairing bybone tissue engineering.