Patients Radiation Doses In Cardiovascular Intervention Operation And Associated Radiation Damage

Objective: To measure the various types of cardiovascular interventional patientssuffered in the process of interventional X-ray radiation dose and fluoroscopy time andanalyze radiation dose to investigate the chromosome aberration and micronucleus rate, todiscuss the factors affecting the radiation dose and to reduce the radiation damage methodin order to strengthen the radiation protection.Methods:1.442cases undergoing cardiovascular interventional procedures collected inFirst Affiliated Hospital of An-hui Medical University, Department of Cardiology areanalyzed. The patients’ area dose product DAP values and Cumulative skin entrance dosesCD values and fluoroscopy time parameters are compared. Patients radiation dose of A, Band C operators are compared.2.100cases of patients peripheral blood withcardiovascular interventional are collected and divided into preoperative and postoperativeself-control. The radiation doses were recorded after operation. With the patient radiationdoses they are divided into four groups including less than0.5Gy group,0.5to1.0Gygroup,1.0to2.0Gy group, and2.0Gy above group. Each group of patients preoperativeand postoperative lymphocyte chromosome aberration and micronucleus rate are tested.Results:1. Different cardiovascular diseases involved in the operation the patients’radiation dose varied significantly. Fluoroscopy time and radiation dose of Congenitalheart disease and coronary angiogarphy were shorter, but percutenous coronaryintervention and radiofrequency ablation were longer. Among various types ofcardiovascular interventional procedures percutenous coronary intervention was thebiggest in cumulative skin entrance dose and dose area product. Radiofrequency ablationwas the longest in fluoroscopy time. In patients radiation dose of three operators A islower than B and C. Referencing standard in accordance with the ICRP dose classification,children radiation dose in cardiovascular interventional procedures was small, and only 2.1%of children with CD value are more than1.0Gy. In the radiation dose in postoperative2h,24h,72h chromosome aberration and micronucleus rate compared with thepreoperative,<0.5Gy group are not statistically significant and the other three groups werestatistically significant (P<0.05), while>2.0Gy group increased significantly comparedwith the preoperative (P<0.01). In postoperative2h,24h,72h4groups compared with eachother,>2.0Gy group of chromosome aberration and micronucleus rate was significantlyhigher than other groups (P<0.05). Compared with0.5to1.0Gy group and <0.5Gy group,the rate of chromosome aberration and micronucleus rate of1.0to2.0Gy group increasedsignificantly (P<0.05). Postoperative rate of chromosome aberration and micronucleus ratein percutenous coronary intervention are significantly high. Parts of complex atrialfibrillation radiofrequency ablation surgery in patients have chromosome aberration andmicronucleus.Conclusions:1. The cardiovascular interventional radiation dose is influenced by manyfactors, including severity, operation of surgical proficiency and fluoroscopy time.2. Partof cardiovascular interventional patients had chromosome aberration and micronucleus.The chromosome aberration rate and micronucleus rate of patients increased withincreasing radiation dose.3. Radiation is inevitable in the cardiovascular interventionalprocedures. Children radiation dose is small, but the sensitivity of the radiation damage islarge. The key is enhancing the dose awareness of operators and shortening the patients’exposed time to reduce the radiation dose ensuring the quality of operation.