The Relation Between Central Aortic Pressure And Abnormal Circadian Rhythm Of Blood Pressure: A Study In Patients With Essential Hypertension Patients

Objective: To investigate the relation between central aortic pressure and abnormalcircadian rhythm of blood pressure in patients with essential hypertension (EH) and theinfluence factors of this by comparing the differences of central aortic pressure inessential hypertension patients with different circadian rhythm. Methods:190patientswhich was selectd from September2009to February2011during the treatment in theFirst Affiliated Hospital of Xinjiang Medical University with essential hypertension wereselected in this study and96patients were male while94were female. Observed thecircadian rhythm and calculated the declining rate of blood pressue. All the patients weredivided into anti-dipper group (nocturnal blood pressure decline rate＜0, n=59), non-dipper group (rate of decline in nocturnal blood pressure≥0and＜10%, n=73), dippergroup (nocturnal blood pressure fall rate≥10%and＜20%, n=8); Test CAP and reflectedwaves gain index (AI), ankle-brachial pulse wave velocity (baPWV) and ankle-brachialindex and the relationship between the difference between. Results: Central artery pulsepressure for each additional10mmHg, reverse dippers hypertension increases the risk to1.13times(OR=1.13,95%CI=1.04~1.11, P＜0.05); Central artery AIx75increases10,reverse dipper hypertension increases the risk to1.26times (OR=1.26,95%CI=1.00~1.09,P＜0.05); baPWV of central artery is related with hypertension in anti-dipper group (P＜0.05). Conclusion: Central artery pulse pressure is related with nighttime declining rate ofblood pressure and associated with anti-dipper hypertension to some extent.