Effect Of Minimally Invasive Aspiration In Treatment Of Massive Intracerebral Hemorrhage

BackgroundIntracerebral hemorrhage is a serious acute cerebrovascular diseasewith high incidence, mortality and disability. The efficacy of traditionalconservative approach and conventional open craniotomy have been verydisappointing. Recently, the appearance of the minimally invasive aspirationhas lightened the treatment of intracerebral hemorrhage. However there arefew studies on the minimally invasive aspiration in patients with massiveintracerebral hemorrhage. So, we planned to examine the effect of theminimally invasive aspiration for massive intracerebral hemorrhage andprovided useful information for clinical work.ObjectiveTo compare the efficacy of the minimally invasive aspiration andtraditional conservative approach in patients with massive intracerebralhemorrhage and explore the clinical therapeutic effect of the minimallyinvasive aspiration.Methods A total of53patients with massive intracerebral hemorrhage in thedepartment of neurology of the First Affiliated Hospital, Chongqing MedicalUniversity from January2008to December2010were enrolled in this studybased on inclusion and exclusion criteria. These patients were randomlydivided into operation group (n=23) and control group (n=30) according totreatment method.Patients in operation group were treated with theminimally invasive aspiration,while patients in control group were treatedwith traditional conservative approach.The curative effect and complicationsbetween the two groups were analyzed at30days after treatment.ResultsThe mortality in operation group was significantly lower than that in thecontrol group (34.78%vs63.33%), there was a marked difference betweenthe two groups (p<0.05). The mortality of patients whose hematomavolume≥80ml or GCS score <9in both groups were100%. No statisticaldifferences were found in effective rate, Barthel Indexes scores andcomplication rates between the two groups at30days after treatment(p>0.05).ConclusionThe minimally invasive aspiration can reduce mortality in patientswith massive intracerebral hemorrhage, it is a simple feasible andminimally invasive therapeutic method. But the curative effect of patientswhose hematoma volume≥80ml or GCS score <9is poor.