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Study On The Qualitative Identification And Quantitive Determination Of Anti-Itching Capsule

Posted on:2013-10-08Degree:MasterType:Thesis
Country:ChinaCandidate:Y ZhangFull Text:PDF
GTID:2234330374978376Subject:Drug Analysis
Abstract/Summary:PDF Full Text Request
Itching capsule prescription is clinical experience prescription for itching disorders, the old doctor of traditional Chinese medicine for many years of clinical use, obvious effect, medication safety. Pruritus compared simple clinical performance, diagnosis is more easily, no matter in traditional Chinese medicine, western medicine have agreed that the etiology of this disease is multifactorial, there may be systemic, may also be localized, is likely to be endogenous, also may be exogenous. Therefore, for this disease, we must find the cause first, for different reasons, administer thoroughly, internal and external treatment, have a definite object in view of the treatment process. Only in this way, we can receive the perfect efforts.Itching capsule is composed of Radix Sophorae Flavescentis, Salvia miltiorrhiza, Rhizoma Chuanxiong, radix paeoniae rubra, Fructus Xanthii, thorns, Tribuli Fructus of seven herbs, with itching effect, activating blood circulation to dissipate blood stasis, anti-inflammatory analgesic, anti putrefaction efficiency. The main clinical for itching that cause from many reasons. Such as the wind, the viruses, psoriasis and other skin pruritus caused disease treatment. The party after years of clinical verification, to a variety of causes itching skin have a very good effect, and small side effect, safe and reliable.The test according to the nature of medicine, as well as their interaction into account, the maximum retained its efficacy case, the extraction method were modified and improved, and the qualitative identification and content determination made reference test. In order to ensure the quality and efficacy, the test on the prescription of the four extraction methods contrast test, select the most suitable extraction method, and the extraction method of the test factors were statistically considerations, to the content of tanshinone Ⅱ a is an index to evaluate the comparative. Then by thin layer chromatography (TLC), the other in the medicine for qualitative identification; using high performance liquid chromatography (HPLC), paeoniflorin and tanshinone II A content as the index, content determination. At the end of the sample solution preparation for48hours on stability. The results show that the processing method is simple and feasible, the nature is stable, controllable quality, effective material retained completely; qualitative identification, content determination method to select the reasonable, simple operation, suitable for the party.
Keywords/Search Tags:Itching capsule, Pruritus, Qualitative Identification, Quantitive Determination
PDF Full Text Request
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