The Cerebral Hemorrhage On Susceptibility Weighted Imaging After The Superior Sagittal Sinus Thrombosis

Objective:To evaluate the variation of medullary veins in patients and its correlation with cerebral hemorrhage after the superior sagittal sinus thrombosis by using susceptibility weighted imaging (SWI) at3.0T magnetic resonance imaging. Metheds:Retrospective analysis the imaging data of14cases of superior sagittal sinus thrombosis by DSA/clinical confirmed and14healthy volunteers, Gender and age were matched between the two groups. All examinations were performed on GE signa HD3.0MRI scanner (General Electric medical systems,USA) with8-channel array coil. Conventional MRI techniques and SW imaging sequence and Magnetic resonance venography(MRV)was used in this study. SWI images were analyzed by the computer processing software and the corrected phase images and magnitude images were obtained.The conventional MR sequences used were as follows:(SE) T1-Weighted images FLAIR(TR2580ms,TE23ms, TI860ms)、(FSE)T2-Weighted images(TR4600ms TE110ms),T2FLAIR (TR9602ms TE117ms TI2400ms) and enhanced T1WI. The slice thickness=5.0mm,FOV=240mm X240mm, and slice interval was1.5mm. SWI parameters were following:TR32ms; TE22ms; FA15; slice thickness=2mm;matrix size=320×384;FOV240mm×240mm. Volume scanning module center before and after the joint connection consistent layer blocks were collected from60layers. the original phase images and magnitude images were obtained by the SWI scanningThe data was transported to adw4.3workstation and the SWI image was post-processed by the Functool software. The original phase images by phase-aliasing and background magnetic field is subject to phase unwrapping and high pass filter, the filter selection of32×32, The corrected phase image was formed the phase value of the corrected phase image range from-π to+π.3-D MIP software was applied to correction diagram of the magnetic moments of the minimum intensity projection-axial MinIP (SWI-MinIP). Observed the cerebral hemorrhage and select the white matter regions with increased and expansion medullary veins by naked eyes in the corrected magnitude images. The same location of the corrected phase image was considered the lesion group, the same level of the lesion at mirror symmetry as the control group1,The control group2was selected as the same level position, size, shape in white matter regions with lesion group. Measuring and analysising the phase value of the selected white matter regions. The selected white matter were marked by oval-shaped with area221-597mm2. Observe and analyze the number, location and area of brain hemorrhage, and the relation with the variation of medullary veins.Statistical analysis software SPSS17.0was used in this study.Using the R×C table data to analysis the sensitivity of secondary hemorrhage in the brain at T1WI-FLAIR, FSE-T2WI and T2-of FLAIR and SWI sequence. One-way analysis of variance was used to compare the phase values of white matter areas with increased and expansion venous (lesion group) with the contralateral white matter areas (control group1) and the same location of healthy volunteers (control group2).Result:12cases with cerebral hemorrhage in the14cases of superior sagittal sinus thrombosis were detected by SWI sequence, the appearance rate is85.71%.One patient with Single site, multiple tumors11cases (sided with2cases, multi-hair with9cases);11cases of bleeding were located in the brain hemisphere, located in the cerebellum with0cases, the brain and cerebellum involvement with1case,0case involved the brainstem.the total number of brain hemorrhage was47by SWI sequence detected,and T1WI-FLAIR detected22, FSE-T2WI detected25, T2WI-FLAIR detected23, than of T1WI-of FLAIR, FSE T2WI, T2WI-FLAIR sequence the number of detected cerebral hemorrhage by the SWI sequence was significantly increased than other sequences (P <0.05).For the selected43white matter areas with increased and expansion medullary veins, the phase values are from-0.571to0.104, the average is-0.051. For the control group1,the phase values are from-0.047to0.079, the average is0.010. For the control group2, the phase values are from-0.045to0.056, mean0.014. The phase values of lesions are significantly lower than the control group1and group2(p<0.05). There was nc significant difference of phase values between control group land group2(p>0.05). the number of Cerebral hemorrhage occurred in the medullary veins expansion areas was41The hemorrhage expansion occurred in the medullary veins by the conventional sequencd and the more obvious expansion of medullary veins,The larger bleeding. No direc correlation between six microbleeding lesions and medullary veins expansion.Conclusion:1. The incidence of cerebral hemorrhage after superior sagittal sinus thrombosi: was85.71%;2. the sensitivity of cerebral hemorrhage after the superior sagittal sinus thrombosi can be displayed by Susceptibility weighted imaging (SWI) is higher than MP conventional sequences.3. The increase and expansion of medullary veins can be displayed b Susceptibility weighted imaging (SWI) and quantitative information can bi provided by the phase value.4. the site and area of cerebral hemorrhage and the scope and extent of medullar veins expansion are basically the same, there may be a positive correlation.