The Clinical And Experimental Research Of JieDuTongLuo To Controll The RS After PCI

Objective: Studying the pathogenes and treatment methods of RS afterPCI from clinical and experimental aspects is to find new research ideas andtreatment prescriptions.Methods: From the literature and teacher years of clinical experience, Wepropose the pathogenesis of RS after PCI is mainly "toxic stasis each knot" hypothesisand develop JieDuTongLuo side.50clinical patients after PCI are divided intotreatment and control groups for comparative study, both groups are1month of treatment,followed up for6months; experiment is observed from the prescriptions of cultured ratvascular fibroblasts proliferation and some cytokines to verify the proposed hypothesis,such as NO and ET-1.Results: The clinical study shows JieDuTongLuo treatment group can significantlyimprove the clinical symptoms and reduce the recurrence rate of angina, increasing leftventricular ejection fraction, reducing high-sensitivity C-reactive protein than in thecontrol group. Experimental studies shows that JieDuTongLuo side inhibits vascularproliferation of fibroblasts, while reducing the ET-1, increasing NO levels, improvingvascular fibroblast metabolism, and helping prevent the occurrence of RS after PCI.Conclusion: JieDuTongLuo side can effectively prevent the occurrence of RS afterPCI. It is not only deepening the knowledge of pathogenesis,but also presentingnew research ideas and treatment prescriptions of the disease,enriching the treatment ofthe disease.