| Objective: Clinical manifestations of unexplained gastrointestinal diseases(such as: gastrointestinal recessive and dominant bleeding, abdominal pain,diarrhea, weight loss, etc) is more and more common. We often can not find thecause by ordinary electronic gastroscopy and barium meal, such as endoscopicand imaging diagnosis, comprehensive observation of the diagnostic equipmentcan not be intuitive to the small bowel; so the diagnosis of this blind spotdiseases of the digestive tract is difficult for the clinicians. Looking for adiagnostic equipment for small bowel diseases has been the ideal. In recentyears, capsule endoscopy (endoscopy as capsule CE) solve this problem, itbring the gospel to clinicians and patients. CE is wireless, painless,non-invasive, non-cross-infection,and does not affect the normal work and restof the subjects.it is a new type of micro-imaging diagnosis and treatment tools,and will make up the traditional digestive endoscopy. CE can not likegastroscopy, as can carry out water supply to the gas and attract otheroperations, so check for bowel preparation before the good or bad will directlyaffect CE image quality. Precisely because of this, the CE becamegastrointestinal endoscopy before bowel preparation the most demanding; but there are no generally accepted CE bowel preparation medication guide. Thepurpose of this experiment under study is to seek an ideal bowel preparation toimprove the quality of capsule endoscopy images, thereby improving itsintestinal diseases diagnosis rate, the better so that the majority of the patientsuffering from intestinal diseases early treatment. Methods:45cases of capsuleendoscopy and eligible patients were randomly divided into3groups, group A(sodium phosphate group), group B (15cases in A group based on thecombined two dimethicone powder), group C (15cases in B group based onthe combined mosapride) in15cases; in all subjects after swallowing capsulesby calculating the time observation capsule into the umbilical region (ilealsegment) provides all image; image (the amount of bubbles, the digestive fluidvolume, digestive fluid cleanliness and the overall observed effects) weresubjective impression graded and quantitative analysis. And find the average.Then the average image graded of each patient make statistical analysis.Statistical analysis of the statistical software SPSS13.0, Measurement data ofbetween groups adopt mean±standard deviation indicate. The comparisonbetween the three groups, the ONE WAY ANOVA analysis. P<0.05assignificantly, P>0.05for was not statistically different. Results: The amountof bubbles in group A is more than in group B and group C，thedifference was significant different (P<0.01). the amount of bubbles ingroup B and group C were not statistically significant (P>0.05). The digestivefluid volume in group C less than in group A and group B, the difference was significant different (P<0.01). The digestive fluid volume in group B less thanin group A, the difference was significant different (P<0.01). Digestivefluid cleanliness in group C is more clear than A and B group, the differencewas statistically significant (P<0.01); Digestive fluid cleanliness in group B ismore clear than A, the difference was statistically significant (P<0.01).Theoverall effect observed in group C has not any interference and is better thangroup A and group B, the difference was statistically significant (P<0.01). Theoverall effect observed in group B is better than group A, the difference wasstatistically significant (P<0.05).Conclusion:(1) C (sodium phosphate+dimethicone powder+mosapride dispersible tablets) has good effect ofremoving bubble, high cleanness, low cost, good tolerance, so that the majorityof the patients and healthy subjects are easy to accept, is ideal methods forbowel preparation.(2) Dimethicone powder applied ideal effect of curingbubble.(3) combined with Mosapride dispersible tablet make the wholeobservation effect improved.Mosapride dispersible tablet is a selective5-HT4receptor agonists in gastrointestinal motility agent. because of5-HT4receptordistribution are run and small intestine intestine is narrower for adverse capsule,so the shortened bowel movements at the same time but then small boweltransit time did not significantly affect the whole digestive tract. Only makesthe observation of the CE of the small intestine is still more comprehensive anddetailed, basically do not miss the detection rate of subtle lesions of the smallintestine. meanwhile shorten the whole small intestine through time due to increased peristalsis, solve the problem of insufficient battery power leads tothe unfinished total small bowel examination. |
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