Unexplained Recurrent Miscarriage Immunotherapy Clinical Analysis

Goal comparison tradition therapy:Huang Titong+HCG, the active immunization lymphocyte active immunization unites Huang Titong+HCG and IVIG passive immunity union therapy+HCG treats URSA the curative effect.Discusses the clinical practical plan. Method:From January,2008212example reason unclear recurrence which receives a medical examination to August,2011miscarries the (URSA) patient to take the object of study.The diagnosis for seals up the immune body negative result the patient, the first group of routine treatment, Huang Titong the+chorion presses the gonadotrophic hormone (HCG) treatment, the second group of passive immunity treatment, the small dosage intravenous injection immune globulin, after Yu Yunqian, is pregnant to the patient good vein drop note, causes it to have the passive immunity union routine treatment treatment.The third group of active immunization treatment, takes her husband or other people circumference venous blood, after the separation lymphocyte Yu Yunqian, is pregnant the hypodermic injection in the patient forearm, causes it to have the active immunization union routine treatment treatment. Observes its pregnancy to16weeks results. Finally:Routine treatment76examples, pregnancy22examples,(success ratio28.9%), passive immunity union therapy70examples, pregnancy36examples,(success ratio51.4%), active immunization union therapy66examples, pregnancy48examples,(success ratio72.7%). Active immunization combined treatment group HCG pregnancy success rate was significantly higher than the passive immune therapy group co-HCG and progesterone+HCG treatment group, statistically significant difference (P<0.05); husband LC LC active immunotherapy with others the success rate of pregnancy no significant difference,(P>0.05); active immunization LC closed joint HCG antibody-positive after treatment pregnancy success rate was significantly higher than the blocking antibody negative, statistically significant difference (P<0.05).Conclusion:The active immunization treats URSA simply feasible, the pregnancy success ratio is high, clinical curative effect safe reliable, surpasses the routine treatment and the passive immunity union routine treatment, is worth referring to the application in the clinical URSA treatment.