The Application Of MR Diffusion Tensor Imaging In Diffuse Axonal Injury

ObjectiveTo investigate the significance of MR diffusion tensor imaging (DTI) in diffuse axonal injury (DAI).MethodTo analysis57patients, including26patients are in acute period of DAI,31patients are in recovery; all the patients are by clinical and imaging material diagnosed. Using MRI scanner superconducting1.5T,8channel head coil scan, DAI group and control group were in magnetic resonance imaging (MRI) scan, then do DTI scan. DAI acute period and recovery and controls were measured each part of the region of interest anisotropic fraction (FA) value, and average diffusion coefficient (DCavg) value, between the two groups of the region of interest corresponding FA value and DCavg value; comparison the acute phase FA and DCavg value with Glasgow Coma Scale (GCS) relevant analysis, recovery phase DCavg value with the FA value with Glasgow Outcome Scale (GOS) relevant analysis.Result1. The FA value of corpus callosum of the control group was the highest, internal capsule hind, moreover is the corpus callosum, the thalamus knee FA value was the lowest. The internal capsule hind DCavg value is lowest, the differences of the corpus callosum ministry and knee DCavg values are not quite, double hemisphere each of the area of interest DCavg values, the differences were not statistically significant (P>0.05).2. There is significant deviation of the FA value between the acute group of DAI (splenium of corpus callosum0.560±0.024, genu of corpus callosum0.507±0.014, posterior internal capsule0.615±0.0620, semioval center0.452±0.032) and the control group.The FA value of genu of corpus callosum correlated with GCS well in the acute group(r=0.614,P=0.001); The DCavg value of every region of interest is no correlation with GCS (P>0.05).3. The FA value of the chronic stage of DAI (splenium of corpus callosum0.621±0.021, genu of corpus callosum0.510±0.053, posterior internal capsulen0.623±0.049, semioval center0.457±0.062) was exceeded than the acute stage, but was decreased than control group; The FA value of genu of corpus callosum correlated with GOS well in the chronic group(r=0.735, P=0.000); The DCavg value of every region of interest is no correlation with GOS (P>0.05).4.Diffusion tensor fiber bundle tracer technology (diffusion tensor tracking, DTT) revealed more lesions located in the parts of the corpus callosum, the acute stage19cases occur in the corpus callosum department, DTT revealed3cases of fracture,13cases fiber bundle slightly sparse,3cases have no obvious abnormity.21cases of recovery occur in the corpus callosum, DTT revealed4cases of rupture, and12cases of fiber bundle slightly sparse,5cases with no obvious abnormalities.ConclusionCompare to conventional MRI, DTI can be more sensitive to find the lesion of DAI, FA value can be used to assess the condition of the patient, predict the prognosis of patients.