Sensitivity C-Reactive Protein In Cardio-Renal Syndrome And Its Significance

PurposeTo detect the igh sensitive C reactive protein values in the cardiorenalsyndrome group, common coronary heart disease group and the diabeticnephropathy group are in compare, find the high sensitivity C reactive proteinchanges in cardiorenal syndrome.MethodsThe last two years30cases of patients with cardio-renal syndrome,which12cases of type1,10cases of type2,8cases of type5. Age43-84years,19males and11females. Within three days after admitted to hospital to check highsensitivity C-reactive protein.Which does not include acute myocardial infarcttion, acute cerebral infarction patients.Control group of Coronary heart disease: random sample of30cases ofcoronary heart disease,19males and11females, aged42-82years. They werechronic coronary insufficiency patients, coronary artery CTA diagnosis orcoronary angiography diagnosis, excluding patients with acute myocardial infarction.Control group of diabetic nephropathy: randomly selected30cases ofpatients with diabetic nephropathy, both for stage1-2lesions, without significant coronary artery disease symptoms, abnormal electrocardiogram. Neverhave coronary heart disease diagnosis.The control group (control group): at random30cases of adult healthysubjects, high sensitivity C-reactive protein testing the examination project.The three groups were in the hospital within three days to check blood of highsensitivity C reactive protein.The statistical analysis of each group of ultra-sensitivity C-reactive protein values, and will cardiorenal syndrome group values respectively compare withcoronary heart disease group and the diabetic nephropathy group. To dostatistical analysis to identify the difference between Statistical methods: usingSPSS13.0statistical software for data processing, measurement data are x±s.Between the two groups were compared using t-test, the difference wasstatistically significant (P <0.05).ResultsCardiorenal syndrome group Hs-CRP was significantly higher than that ofcoronary heart disease group, was statistically significant (P <0.05).Cardiorenal syndrome group Hs-CRP was significantly higher than diabeticnephropathy group, there is statistically significant (P <0.05).Ultra-sensitive C-reactive protein of Cardio-renal syndrome group wassignificantly higher statistically significant than that control group.ConclusionsCardiorenal syndrome and high sensitivity C reactive protein aresignificant related.1. Hs-CRP is associated with vascular sclerosis, and vascular sclerosis cause bloodvessels to the inflammatory response.2. Hs-CRP is associated with inflammation of kidney.3.Hs-CRP is associated with the endocrine, nervous, disorders of varioussinflammatory cytokine production.