| Purpose: to investigate the TCM constitutions of patients with heart failure after acute myocardial infarction,and to analyze the distribution of TCM constitutions in patients with acute myocardial infarction.To study the differences of n-terminal forebrain natriuretic peptide,hypersensitive c-reactive protein and coronary artery diseases among TCM constitutions,so as to provide effective evidence and new ideas for the prevention of heart failure after acute myocardial infarction from the perspective of TCM constitutions.Materials and methods:From June 2017-July 2019 in liaoning university of traditional Chinese medicine hospital of hospitalized patients selected within the effective time window accept percutaneous coronary artery intervention treatment of 80 cases of acute ST segment elevation myocardial infarction within 7 days after the diagnosis of heart failure patients as observation group,other 80 cases of acute ST segment elevation myocardial infarction patients who were not diagnosed with heart failure within 7 days after for the control group(group match,namely traditional risk factors such as hypertension,hyperlipidemia and diabetes in the proportion of no statistical difference between the two groups,the onset time and related to the balloon expansion drug usage no significant statistical differences).The constitution of the patients was investigated with the constitution questionnaire,and the distribution law of TCM constitution was analyzed.According to the results of the questionnaire,the TCM constitution was divided into groups and compared.The differences between traditional Chinese medicine constitution and n-terminal forebrain natriuretic peptide(nt-probnp),hypersensitive c-reactive protein(Hs CRP),coronary artery lesion site and the number of involved vessels were analyzed.Results:1 in the observation group and control group,the distribution of phlegm and dampness in 63cases(78.8%),blood stasis in 34 cases(42.5%),Yang deficiency in 32 cases(40.0%)and qideficiency in 26 cases(32.5%)was statistically different(P<0.05).2.In patients with heart failure after acute myocardial infarction,nt-probnp(7688.553±2842.171pg/ml)was higher in the yang-deficiency group than in the non-yang-deficiency group(3986.616±2594.854pg/ml),and the difference was statistically significant(P<0.05).Hs CRP(25.831±2.480mg/L)was higher in the phlegm-dampness group than in the non-phlegm-dampness group(15.353±2.744mg/L),and the difference was statistically significant(P<0.05).3.Among the patients with heart failure after acute myocardial infarction,only the proportion of patients with phlegm and dampness was found to be higher than that of other constitutions with multi-branch lesions,and the difference was statistically significant(P<0.05).Conclusion:1.The majority of patients with heart failure after acute myocardial infarction are of concomitant constitution,with more phlegm and dampness,qi deficiency,Yang deficiency and blood stasis than those with acute myocardial infarction.2.In patients with heart failure after acute myocardial infarction,the level of yang-deficiency nt-probnp is higher,and patients with yang-deficiency syndrome are more likely to suffer from heart failure after acute myocardial infarction.The higher levels of phlegm and SCRP suggested that patients with phlegm and phlegm after acute myocardial infarction were more likely to suffer from heart failure.3.In patients with heart failure after acute myocardial infarction,phlegm and dampness were more common in coronary artery multi-vessel lesions.No significant statistical difference was found between TCM constitution and coronary artery involvement sites. |
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