Effect Of Hyperbaric Oxygen On Spinal Cord Injury And Influencing Factors

Objective: To investigate the efficacy of hyperbaric oxygen treatment ofspinal cord injury as well as factors affecting the efficacy.Methods: Retrospective analysis of China-Japan Union Hospital of JilinUniversity from2009Sep to2013Jan in our hospital diagnosed patients withspinal cord injury. there are123effective cases who underwent decompressionof the spinal cord, nerve nutrition, rehabilitation training and other routinetreatments. According to patients whether receiving hyperbaric oxygen therapy,the patients is divided into A and B two groups.63cases of hyperbaric oxygenis the treatment group and group B of60cases is non hyperbaric oxygentreatment group. Group A according to the degree of spinal cord injury wasdivided into group A1of incomplete spinal injury in48cases,15cases ofgroup A2of complete spinal cord injury. Group A according to the time ofhyperbaric oxygen treatment divided into group A3that hyperbaric oxygentreated with40days in42cases and group A4of hyperbaric oxygen therapy20days in21cases. The group A3according to the intervention time of hyperbaricoxygen was divided into A5, A6and A7group. Group A5of12cases waswithin7days after the onset of hyperbaric oxygen therapy. The20patients inthe group A6was8-14days after the onset of hyperbaric oxygen therapy.10cases as group A7was in the15days after the onset of hyperbaric oxygentherapy. We were overall evaluation the patients’s function of spinal cordfunction and activities of daily living with the American Spinal InjuryAssociation (ASIA) and Spinal Cord Independence Measure (SCIM-Ⅲ)before the treatment and after60days of treatment.Results: A, B two groups were no significant difference (P>0.05).The2groups were significantly improved after treatment (P<0.05). Group A was larger improvement than group B (P <0.05); The group A3was better than thegroup A4（P<0.05）;The group A5was better than the group A6and group A7（P<0.05），and the effect of the groupA6was better than the groupA7.Conclusion: Hyperbaric oxygen therapy was an important auxiliarytreatment of spinal cord injury. Early stages and full courses（more than40days） hyperbaric oxygen therapy could effectively promote the patients withspinal cord injury (especially in patients with incompleted spinal cord injury)recovering of spinal cord functions.