Clinical Analysis Of Typical Osteofibrous Dysplasia

Background:Osteofibrous dysplasia is a rare,fibro-osseous,nonneoplastic condition of unknown etiology that frequently affects the tibia and fibula of the youth.The first published description of oesteofibrous dysplasia dealt with a lesion in the tibia;it was reported in1921by Franghenheim,who named the entity congenital osteitis fibrosa.Campanacci proposed the term Osteofibrous dysplasia of the tibia and fibula for the entity because it suggests a histological similarity to fibrous dysplasia.There are few studies and literiture about this condition,therefore,many cases go misdiagnosed.It makes difference to make this condition clear.Objective:Our study on this condition is to make the conception of osteofibrous dysplasia clear through the comparement between the etiology,clinicle course,pathology of osteofibrous dysplasia and fibrous dysplasia.Another point is to find a better treatment of oesteofibrous dysplasia.Method:From March2003to March2013,a retrospective analysis was performed with20cases of osteofibrous dysplasia in the Qilu Hospital of Shandong University,including the age,gender,location of osteofibrous dysplasia,diagnoses,pathology,treatment and prognosis.Analyse the statistics to find out the better surgical mode. Among the20cases of osetofibrous dysplasia,12cases are male,8cases are female,the sexual rate is1.5:1.The average age of onset is12.6±6.3years.The typical presentation is pain and mass,3cases with pathological fracture.1case was suggested to take cast immobilization,while other19cases underwent curettage.Results:20cases get follow-up from6to117months,the average is53.1 months.1case got delayed union of incision,1case was found rejection.1case was found relapsed when the inner fixation was taken out and the curettage was taken then.1case seemed to recur1year after surgery. The bone graft of14cases get healed.Conclusions:Osteofibrous dysplasia is a unique entity distinguished from fibrous dysplasia.The radiologic characteristic is eccentric,intracortical and oeteolytic lesion in tibia and fibula.The manifestation usually is pain and swelling of tibia,occasionally with pathologic fracture.Osteofibrous dysplasia is totally different from fibrous dysplasia in aspects of etiology,clinical course,radiology and pathology.Osteofibrous dysplasia should be distinguished from fibrous dysplasia,adamantinoma,none-ossifying fibroma and Paget’s disease.The wide curettage is recommended to decrease the recurrence.