Investigation On Iodine Nutrition Of People In IDD Areas In Shandong Province

Objective:Observe iodine nutrition situation of people in iodine-absent area in order to provide the basis for future prevention and cure work.Methods:According to the location selection and distribution of population in5counties (city, area), adopt the method of stratified random sampling, in each county (city, area)2residents collect water samples (water),288households edible salt, collection and pregnant women, lactating women and adult rick a urine or fasting urine,100copies each, select1008～10years old schoolchildren in thyroid ultrasound examination and post fasting urine collection times. To data entry, data using Epi info3.5clean. SPSS18.0is used to the statistical analysis. In various areas between the water iodine and urinary iodine and salt iodine and urinary iodine correlation by using Spearman rank correlation analysis, the measurement data compared with single factor analysis of variance (ANOVA), various rate compared by chi-square test, significant differences of determination standard for P<0.05.Results:10household drinking water samples were tested and the result was0～43.78μg/L with the mean of6.14μg/L. Water Iodine content of each district is different in statistic (P<0.05).1452household salt samples were tested in five counties. The result was0.00～42mg/kg with the mean of27.79mg/kg. The results show such statistical differences among counties (districts) as the rate of qualified iodine salt consumption (90.64), the non-iodine salt rate(5.38), iodine salt covering rate(94.62) and qualified rate of iodine salt (95.79). The differences of salt iodine between Diayue and Juxian, Gaomi and Juxian districts were not significant in statistic by multiple comparisons (LSD method)(P>0.05).And the others districts were significant.(F=25.1, P<0.05)498urine samples of8-10students were tested and the urine iodine result was14.9-2614.7u g/L with the median of235.2μ g/L;320urine samples of18-45fertile women were tested and the urine iodine result was10.4-1757.7μ g/L with the median of231.85μg/L;285urine samples of lactation women were tested and the urine iodine result was14-1486.9μ g/L with the median of182.5μg/L;298urine samples of infants were tested and the urine iodine result was18.3-1451.6μg/L with the median of258.7μg/L;283urine samples of pregnant women were tested and the urine iodine result was12.7-2383.2μ g/L with the median of166.3u g/L.514students of8-10years were examined and the goiter rate was0-2.97%(mean1.75%)by palpation and0-2%(mean1.17%)by B-ultrasound. The volume of thyroid was1.13-7.5ml (2.95±0.72ml), the mean was2.95ml, S. D was0.72.524Intelligence Quotient test were operated and the IQ was11-139, the mean was110.24, S. D was15.14, The differences of IQ between boy and girl were not significant(F=3.2, P>0.05); The differences of IQ between8and9years old were not significant in statistic by multiple comparisons (LSD method)(P>0.05). And the others districts were significant (F=13.9, P<0.05). Conclusion:The iodine nutrition situation of people was suitable and the present concentration in edible iodine-salt could satisfy the requirement of people in different iodine absent area in Shandong province. It is feasible to adjust the present concentration in edible iodine-salt appropriately.