| Objective:To explore the etiology, clinical characteristics and differential diagnosing of hepatic veno-occlusive disease so as to improve the level of diagnosing and treatment.Methods:Analysis of the clinical data of one patient suffered from hepatic veno-occlusive disease, and summarized and reviewed the literature.Design:case report and literature review.Material:A young female patient, who had amenorrhea for one and a half years, and appeared intermittent abdominal distention for half a year, accompanied by weakness and anorexia. However, the symptom of abdominal distension still existed after treatment.Interventions:Relational examinations were carried out such as enhanced computed tomography (CT), hepatic angiography, and pathological examination, so as to make the definite diagnosis. Meanwhile, supportive treatment included liver protection, anti-fibrosis, and diuresis was used. Drugs of liver damage were also discontinued.Results:Enhanced CT showed map-shaped enhancement, and liver pathology resulted in coincidence with hepatic veno-occlusion disease, meanwhile liver cirrhosis developed trend. Finally, hepatic veno-occlusive disease was diagnosed.Conclusions:The diagnosis of hepatic veno-occlusive disease is difficult, which should be combined with patient history, clinical manifestations and auxiliary examination for comprehensive judgment. There is no specific treatment for hepatic veno-occlusive disease, but early prevention and early diagnosis can reduce morbidity and mortality of the disease. |