Combine Traditional Chinese And Western Medicine Treatment Of Merger Pleural Effusion Of Clinical Research At The Surial Of Patients With Nsclc

Objective: To study the advanced NSCLC patients complicated with pleuraleffusion and the influence of clinical characteristics of combination oftraditional Chinese and Western medicine therapy on the survival period.Methods: Retrospective analysis of the death cases,18cases needed chestpuncture on liquid into massive hydrothorax group,16patients without thoracicpuncture on liquid into small chest water group, record and draw the two groupsof patients’ survival time from the appearance of pleural effusion to deathand then compare the survival time of them by drawing survival curves withKaplan-Meier method,then inspect the long-term effects with LogRank(Mantel-Cox) test.then count and analyze two groups of patients’metastasis andthe situation of combination of traditional Chinese and Western medicinetherapy.count data using chi-square test, traditional Chinese medicine usingdescriptive statistical analysis and count the number of cases via describeingchart,Also observe the influence on the patients’ survivaltime with differenttreatments.Results:1、 The patients’survival time with small chest water are significantly shorterthan the patients’survival time with massive hydrothorax group in terms of theaverage and median survival time (P=0.038),respectively,11.0±1.2months vs15.4±1.7months,11vs16months.2、The patients’ with massive hydrothorax group are mostly large pleuraleffusion as the first symptom,the patients’ with small chest water are mostlyassociated with a small amount of pleural fluid and metastasis. Beforetreatment,The patients’ number of metastatic sites with massive hydrothoraxgroup’ appeare more often than those small chest water (P <0.001); before thedeath,the statistics of metastatic sites appearence shows that the patients’with small chest water group have more multiple metastases than the patients’with massive hydrothorax group(<0.001). 3、The combination of traditional Chinese and Western medicine IntegrativeMedicine, in Chinese medicine treatment,The patients’ with massive hydrothoraxgroup have more diuresis medicine,the patients’ with small chest water have less,but the most patients have adjusting qi traditional Chinese medicine;In theWestern medicine treatment,The patients’ treatment with massive hydrothorax ispleural the lien surgery and injecing drug into intrapleural.4、Medicine and Iressa have a longer average survival time compared withtraditional Chinese medicine and symptomatic treatment,traditional Chinesemedicine plus chemotherapy or radiotherapy or chemotherapy and radiotherapytreatment(P <0.05), respectively,18.8±2.5months vs10.8±1.7,18.8±2.5months vs13.3±1.0months.Conclusion:1、Through combination of traditional Chinese and Western medicine therapy,thesurvival time of patients’ with large pleural effusion as the first symptom andless metastasis,is generally longer.2、In traditional Chinese medicine in the treatment of pleural effusion,Professor Yin Dongfeng good at treating pleural effusion through regulatingqi.3、The combination of traditional Chinese medicine and Iressa can significantlyimprove patients’ survival time.