Based On Clinical Epidemiological Investigation Cardio-cerebral Disease Phlegm And Blood Stasis By Each Study

Purpose：To explore the status,affected factors and diagnosis of phlegm andblood stasis syndrome of angina pectoris combined arterial atheroscleroticcerebral infarction.Material and method： Based on the core journals and the Chinese medicinebook,referring to the authoritative standard,repeatedly demonstrated byexperts,we developed epidemiological survey form about angina pectoris combinedarterial atherosclerotic cerebral infarction. The study used thecross-sectional observation and chose11hospitals as sub-centers. Afterexplaining to patients the purpose and the content of the study and signing theinformed consent,we strictly followed the inclusion criteria,exclusioncriteria,exclusion criteria to screen cases.982patients,who met the inclusioncriteria,were one-time collected general information,history ofdiseases,associated risk factors,physical examination,the incidence of solarterms,TCM etiology and four diagnostic information. Based on982cases withangina pectoris combined arterial atherosclerotic cerebral infarction,we usedthe frequency and composition ratio to analyze the status of phlegm and bloodstasis in the incidence of angina pectoris combined arterial atheroscleroticcerebral infarction. Based on cases of phlegm and blood stasis group,non-phlegmand non-blood-stasis group and non-phlegm and blood stasis group,we use thefrequency,chi-square test,t test,logistic regression,discriminantanalysis,ROC curves to explore affected factors and diagnosis of phlegm and bloodstasis syndrome of angina pectoris combined arterial atherosclerotic cerebralinfarction.Results：1. Phlegm and blood stasis syndrome (160cases) was the top one among anginapectoris combined arterial atherosclerotic cerebral infarction disease (982 cases). In the type of compound syndromes,phlegm and blood stasis syndrome(213cases) ranked second after wind phlegm blocking the vessels syndrome(230cases). The syndrome name containing phlegm (574cases) rankedfirst,while the syndrome one containing blood stasis (497cases) second. Thesyndrome name containing both phlegm and blood stasis (298cases) was thetop one among other syndrome names containing two elements.2. Logistics regression analysis: the South,inland,eating partial fatty,BMImight be risk factors of phlegm and blood stasis syndrome of angina pectoriscombined arterial atherosclerotic cerebral infarction.3. After establishing2functions for diagnosis of phlegm and blood stasissyndrome,we evaluated their diagnostic accuracy. Sensitivity,positivepredictive value,negative predictive value for the diagnosis of phlegm andblood stasis syndrome were higher in the function about phlegm and bloodstasis vs. non-phlegm and non-blood-stasis than in the one about phlegm andblood stasis vs. non-phlegm and blood stasis,that is,84.51%,0.34and0.93.Specificity,accuracy,positive likelihood ratio,negative likelihoodratio,Youden’s index and the ROC area under the curve for the diagnosis ofphlegm and blood stasis syndrome were higher in the function about phlegmand blood stasis vs. non-phlegm and blood stasis than in the one about phlegmand blood stasis vs. non-phlegm and non-blood-stasis,thatis,77.76%,77.29%,3.40,0.31,0.53and0.84.Conclusion：1. The study showed that phlegm and blood stasis played an important role inthe incidence of angina pectoris combined arterial atherosclerotic cerebralinfarction.2. This study suggested that the South,inland,coldness and eating partial fattymight be risk factors of phlegm and blood stasis syndrome of angina pectoriscombined arterial atherosclerotic cerebral infarction.3. Based on four diagnostic information,this study established a function for the diagnosis of angina pectoris combined arterial atherosclerotic cerebralinfarction,which could be used for clinical diagnostic reference.