Lk's Dryness Dry Eye Curative Effect Of Decoction Of Research

Primary Sjogren’s syndrome (pSS) is mainly involving the exocrine glands a chronic au-toimmune disease, diseases, clinical incurable diseases. The clinical manifestations of dry eye syndrome, xerostomia, recurrent parotid gland enlargement, dry skin and so on, and often ac-companied by a variety of clinical manifestations of systemic damage, affect the patient’s quality of life, the prevalence of the disease in China approximately0.29%to0.77%, the male to female ratio of1:9. Western medicine is no effective treatment, mainly local symptomatic treatment and active treatment for complications, such as artificial tears, artificial saliva to improve the treatment of local symptoms, the treatment of diseases of DMARDs, biological agents and hormones play a effect, but does not fundamentally improved.There is no similar records of pSS in the ancient literature, and in1980s Chinese medi-cine master Lu Zhizheng is studying Chinese medicine treatment of Sjogren’s syndrome, that belong to the scope of Chinese medicine "dry Bi" Sjogren’s syndrome, and in the years of clinical diagnosis and treatment, and gradually accumulated a wealth of clinical experience that dry paralysis dry from the outside, the internal dryness dryness damage to the blood and body fluids caused Yin-chun, wear and tear, blood deficiency, limb tendons dystrophy, bleed-ing Blockage sputum condensation poly, the context barrier the body fluid compresses barri-ers, resulting in dry eyes and dry mouth, dry skin, limb pain syndromes. The this disease dry crooked potential rampant, and can lead to lung, kidney, liver and other organ involvement.According to the State Medical Master Lu Zhizheng is the treatment of primary Sjogren’s syndrome experience, randomized, single-blind, controlled, prospective clinical trials, re-search to the old Yiqiyangyin law on behalf of parties-Runzao soup as the basic side Differ- entiation Modified clinical programs for the treatment of primary Sjogren’s syndrome, a total sample size of116cases,58cases in each group, the total course set for six months, and achieved good clinical efficacy. The conclusions are as follows:1.Improve dry eye symptoms:Improvement of dry eye symptoms, the two sets of dry eye VAS scores decreased with treat-ment, and the treatment group rapid onset, you can see significant improvement after2months of treatment, significantly better than the control group; two sets of dry eye symptom score decreased with treatment, the treatment group improved significantly, a month after the treatment group before treatment more important than the control group than in control group after treatment, the treatment group than the control group.2.the TCM syndromes total credit Disease efficacy:Both groups significantly reduced TCM syndromes total score, the treatment group from the rapid onset of marked decline after1month, significantly better than the control group, and continued until after6months; efficacy of the disease, the treatment group efficiency was82.76%in the control group, the total effective rate was60.34%in the treatment group than the control group.3. Laboratory indicator:The two groups after6months of treatment serum IgG water average decreased significantly, indicating that the the moistening soup certain inhibitory effect on serum IgG. The rest of the immune, inflammatory markers have improved to some extent, but no significant difference.4.ink absorption test:After6months of treatment, the treatment group left eye ink absorption test, significant im-provement in the left eye of the control group did not improve significantly, indicating that the the moistening soup can improve patient Schirmer; right eye improved treatment group, but the difference is not obvious needs further study, in order to more fully reflect the true effica-cy.5.Security aspects:After treatment, white blood cells, platelets, alanine aminotransferase, aspartate aminotrans-ferase, creatinine, blood urea nitrogen compared with before treatment were not statistically significant. The treatment group and the control group, the incidence of adverse reactions was1.72%(1/58),22.41%(13/58); expulsion rate was1.72%(1/58),24.14%(14/58). Control group, adverse reaction rates and shedding were significantly higher than the treatment group, indicating that the treatment group security is more good.This study demonstrated that the The Road’s Runzao soup a significant improvement in the role of PSS patients with dry eye symptoms, while reducing the level of serum IgG, and the clinical application seeurity.This study the pSS Chinese medicine treatment of Chinese medi-cinc formulations lay a good foundation for further study,the clinieal evidence for the effica-cy of Chincse medicine treatment of ailments advantage.