| Objectives:Based on influences of different load swimming movements on soleus wet muscle weight, protein content, androgen content and AR content, this thesis is to find out which kind of load movement is more suitable to the recovery of muscular atrophy, analyze the total muscle protein content and the change of androgens and AR content in the same load movement, study the changes of soleus muscle protein content, androgen content and AR content and also its relationship with the recovery of muscular atrophy in different load movements, discuss the possible mechanism of the muscular atrophy. The research of rats aims to provide reference for exercise recovery after human muscular atrophy.Methods:42healthy SD male rats, having been fed adaptively a week, were randomly divided into6groups, each of those groups including7rats. All the rats are numbered and weighed. Group A is the natural control group. Group B, the suspension control group, has been suspended from the second week to the end of the experiment. Group C, was suspended for2weeks from the second week and then rested for five days (diet and water are available during the first three days, after15min two days of swimming to adapt to training). During the next four weeks, rats will carry on weight-free swimming and be trained for six days in a week and once per day, with the water temperature of (32±1)℃. Group D was suspended for2weeks from the second week and then rested for five days (diet and water are available during the first three days, after15min two days of swimming to adapt to training). During the next four weeks, rats will carry on2%-weight-bearing swimming and be trained for six days in a week and once per day, with the water temperature of (32±1)℃. Group E was suspended for2weeks from the second week and then rested for five days (diet and water are available during the first three days, after15min two days of swimming to adapt to training). During the next four weeks, rats will carry on5%-weight-bearing swimming and be trained for six days in a week and once per day, with the water temperature of (32±1)℃. Group F: from the first2weeks, suspended for2weeks rest to adapt to5days (3days free diet water, after15min two days of swimming to adapt to training). Then for four weeks incremental swimming exercise:First week, training6days.30min per day; second week, training6days,60min per day:third week, training6days,90min per day;fourth week, training6days,120min per day. All of the rats free diet and drink, group C. D and E’s exercise time are according to the pre-weight-bearing rats produces5%of body weight exhaustive swimming time identified as2hours.6groups of rats were taken weight scales after finishing the swimming the next day, uniform slaughter take soleus muscle, the muscle wet weight scale to take and record. Soleus muscle protein content, androgen content and AR levels of rats in each group were measured and the results were analyzed statistically by SPSS15.0software.Results:The weight of rats that have hanged for two weeks decreased a lot (P<0.01) when compared with their weighs before the suspension. Compared with Group A, those rats’ weight decreased to a great extent (P<0.01); Suspension after2weeks, adaptability to rest5days can make rats weight very significantly increased (P<0.01), Compared with Group A, weight decreased very significantly (P<0.01); Suspension control group B and the blank group A comparison, SWW decreased very significantly (P<0.01). SPC, SAC, SARC are fallen, but no significant difference (P>0.05); Rats SWW and W have a positive correlation, and ratio is closer to, no significant difference (P>0.05); The first week after the movement, group C’s weight increased significant (P<0.05), group E and F’s weight very significant increased (P<0.01),2weeks after the movement, group F’s weight significantly lower (P<0.05), the third week after motion, group D and F’s weight significant increased (P<0.05),4weeks after exercise, group D’s weight significantly lower (P<0.05), sports group of each movement period weight have no significant difference (P>0.05), Compared with Group A has no significant difference (P>0.05), but in the first week after the movement, group D and B have significant difference (P<0.05):4weeks after the movement, group E and B have significant difference (P<0.05):After the end of the exercise, the exercise groups*SWW and A’s contrast, there was no significant difference (P>0.05). but B contrast, increased significantly (P<0.05). group C. D and F have very significant increase (P<0.01); The exercise group’s SPC and SAC compared with group A and B have no significant difference (P>0.05); The exercise group C. E and F’s ARC ompared with group A and B have no significant difference (P>0.05). but group D and group A contrast significantly lower than A group (P<0.05):Different period to rats’weight has a very significant influence (P<0.01). different samples to rat’ weight has no significant influence (P>0.05). different groups to rat’s weight has a very significant influence (P<0.01). different period of different sample to rats’ weight has no significant effect (P>0.05). different period of different groups to rat’s weight has no significant effect (P>0.05). different groups of different sample to rats’weight has very significant influence (P<0.01); Group E’ movement is most favorable to the rat’s soleus muscle atrophy recovery. |
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