Different Intensities Of Exercise On The Growing Season In Male Rats Androgen Levels And Quadriceps Androgen Receptor Gene Expression

The physiological functions of androgen and androgen receptor are very extensive. They have specific effects on the target organ and the sensitive tissue. The androgen and androgen receptor level can be influenced by many factors such as the process of metabolism, individual exercise capacity et al. In this article, we probed into the influence of different training intensity on androgen and gene expression of androgen receptor of quadriceps femoris in puberty rats and aimed at providing some theoretical basis for the exercise training of youth.70 SD rats,4 weeks of age, were assigned randomly to three groups: baseline control, exercise and control. The exercise group was divided respectively into low leading exercise and high loading exercise subgroups and 6 , 9 weeks exercise subgroups. Both groups were treadmill-trained for 6 weeks and 9 weeks respectively, Sd/week ,60min/day. After training , blood and muscles are collected for the test of serum T, quadriceps femoris T, quadriceps femoris AR mRNA and protein content.The results showed that the serum T and quadriceps femoris T increase in the low intensity group, the serum T of the high intensity group increase in the growth spurt period (6 weeks group) and much lower than the low intensity group in 9 weeks group, but it is still much higher than the control group.The quadriceps femoris T of the high intensity group increase in the growth spurt period .The expression of AR mRNA of quadriceps femoris increase with aging before and after the growth period. ARmRNA increase in both high and low intensity group which is consistent with T level. The quadriceps femoris T decrease in high intensity group with 9 weeks training, ARmRNA level are significantly higher than the control group. Presumably it is caused by the compensatory affect of our body.(4) there is no difference in the protein content of high and low intensity group. This result indicates that the training load in this experiment has no effect on the protein content of quadriceps femoris muscle tissue.