Synthesis Of Novel Photoresponsive Molecularly Imprinted Polymer Microspheres With Special Binding Properties

This manuscript describes a novel light controllable composite microsphere. The photoresponsive molecularly imprinted microspheres were firstly prepared by grafting azo-containing functional monomers onto the surface of silica particles through surface polymerization. The microsphere which takes silica gel as carrier, an azo-containing compound as functional monomer,2,4-D works as molecular template synthesized via silica gel surface polymerization. The spherical photoresponsive SMIP particles have higher selectivity、better adsorption properties and also have the properties to release and take up the targeted molecule by light.The main component of the experimental study(1). In this study, an azo-containing functional monomer was successfully fabricated. The novel azo-containing functional covalently bond at one end to3-Iodopropyltrimethoxysilane and one end to the template which have oxhydryl group, carboxyl group by intermolecular forces-hydrogen bond.And the Infrared Spectroscopy and nuclear magnetic resonance spectrum were used to observation the functional monomers.(2). The photoresponsive molecularly imprinted polymer was synthesized by molecular imprinting technique. The photoresponsive molecularly imprinted polymer was obtained by taking silica as a carrier, AIBN works as initiator, EGDMA as cross-linking agent. The Infrared Spectroscopy (FT-IR) and scanning electron microscopy (SEM) were used to characterize for research of the surface morphology and structure of polymer materials prepared.(3). Application and performance were explored on imprinted polymer materials prepared. The result of photoisomerization experiment demonstrated that the azo-containing SMIP can release and uptake of Binding experiments showed that the photoresponsive molecularly imprinted polymer have a better binding capacity then its related compounds. Scatchard analysis illustrated that the template-polymer system showed two sites binding behavior, including both specific binding and non-specific binding by hydrogen-bond interaction, the specific binding Kd and Qmax have been calculated to be0.054mmol·L-1and0.167mmol·g-1. In order to confirm the specific adsorption of imprinted molecular polymer, non-imprinted polymer works as reference substance, the result indicate that the imprinted polymers have specific recognition, but non-imprinting polymers not. There were33pictures,14tables and66references in this paper.