| Water dispersible granule is a kind of green environmental compatibility, low toxicity and high dosage form better, more and more countries pesticide developers and manufacturers favor, is a new dosage form with good development potential.This paper mainly60%Dimethomorph as the research object, through early experience try method for screening a performance more excellent water dispersible granule formulation, and on the basis of the additives were optimized by screening test, flow point method to selection of wetting agent, and orthogonal design was adopted to optimize the dispersant, binder, disintegrating dosage, the three formula of water dispersible granule quality standard. In addition, the water powder preparation granule was studied, the study found, water dispersible granule processing technology, quality selection, drying temperature, drying time and other factors will cause varying degrees of impact on the60%Dimethomorph water dispersible granule preparation, the main research results:1.60%Dimethomorph water dispersible granule best formula is:Dimethomorph content is60%, the content of SP-2836is5%, the content of GY-D90is5%, dextrin content is0.6%, the content of L-HPC is1%, up to100%carrier. The water dispersible granule quality control testing standards, the composition and the preparation of disintegration time was425, floating rate is94%.2Selection of wetting dispersant on the suspension rate influence. Dispersant NNO compared with dispersing agent GY-D900and GY-D10are poor, then two kinds of Dispersant Effectiveness difference.3Dispersants GY-D900+Morwet-D425can reduce the surface tension of larger, and the dispersing agent GY-D900+GY-D10, dispersant GY-D900, the effect of dispersant GY-D900+SP2836show is not very ideal.4In the preparation of drying steps, the drying temperature is higher than100degrees Celsius, the drying time should not be too long, otherwise it will prolong the disintegration time of preparation. |
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