| Aim of study: Animal fat not only has the role of energy storage, but also has the role of the body’s endoc-rine tissue. The effect of different animal fat on the body has been reported, however, most of conclusionsare lack of the support of animal physiology experimental data. This paper intends to study the physiologic-al and biochemical function in rats by preparative ovine, swine, bovine, equine fatty oil and oral rats plas-ma lipids, in order to understand of the characteristics of the respective roles and lay a physiological basisfor the development and utilization of animal fat resources.Materials and methods:130male SD rats were randomly divided into5groups, namely, basic control,ovine fatty oil, swine fatty oil, bovine fatty oil and equine fatty oil group, each of which was divided intothere sub-group fed with different doses of fatty oils, namely, high(2mL/100g. bw), medium(1mL/100g.bw) and low dose(0.5mL/100g. bw), and the control group was fed with purified water(1mL/100g.bw) int-ragastrally. After56-day feeding experiment, the body weight change, the visceral fat weight, organ coeffi-cients, the number of red and white cells, plasma glucose(GLU), four plasma lipids and changes in blood f-actors associated with lipid metabolism, four plasma lipids, i.e., high density lipoprotein(HDL-C), Low de-nsity lipoprprotein(LDL-C), Cholesterol(TC), Triglyceride (TG), in blood factors associated with lipid me-tabolism, i.e., Insulin(INS), Leptin(LEP), nitric oxide(NO), superoxide dismutase(SOD), Malondialdehyde(MDA).Result: Four animal fatty oils had no significant effect on weight, the number of red cells, the heart organcoefficient, LEP, NO(P>0.05). However the visceral fat weight in rats fed with high doses of different fattyoils as well as in rats fed with medium dose of swine and equine fatty oils was increased significantly(P<0.05). The liver organ coefficient was extremely increased in rats feeding with high dose of swine and equinefatty oils(P＜0.01); the spleen coefficients were extremely decreased in rats feeding with high dose of diff-erent fatty oils(P＜0.01), and decreased significantly in the rat feeding with medium and low dose of bovi-ne fatty oil(P<0.05); the lung organ coefficient was extremely decreased in rats feeding with ovine fatty oil(P＜0.01); the kidney organ coefficient was extremely decreased in rats feeding with bovine fatty oil, highdose of ovine, swine and equine fatty oils(P＜0.01), and decreased significantly in the rat feeding with me-dium dose of ovine fatty oil(P<0.05), and only low dose of ovine fatty oil could extremely increased the ki-dney organ coefficient(P＜0.01). The number of white cell was extremely increased in rats feeding with di-fferent animal fatty oils(P＜0.01). The plasma glucose content was extremely increased in rats feeding withmedium dose of ovine fatty oil, high and medium dose of equine fatty oils than the control(P<0.01), and si-gnificantly increased in the rat feeding with low dose of ovine fatty oil and high dose of bovine oil(P<0.05).The plasma HDL-C content in the rat feeding with high dose of ovine fatty oil was significantly increased(P<0.05), and extremely increased in the rat feeding with high dose of swine fatty oil(P<0.01), whereas onlyhigh dose of bovine fatty oil feeding stimulated rat’s LDL-C increasing significantly(P<0.05). The plasmaTC content in rats feeding with either bovine or equine fatty oils was extremely increased(P<0.01), and on-ly high dose of ovine fatty oil could stimulate the TG increasing significantly (P<0.05). The insulin was ex-tremely decreased in the rat feeding with high and medium dose of equine fatty oil(P<0.01). The melondia-ldehyde was extremely decreased in the rat feeding with ovine and swine fatty oils(P<0.01). The superoxid-e dismutase was extremely decreased in the rat feeding with bovine and equine fatty oils(P<0.01).Conclusion: Four animal fatty oils had no effect on weight, the number of red cells, the heart organ coeffi-cient in laboratory studies, different animal fatty oils on the other physiological indicators of the rat trend ismore consistent: different animal fatty oils all increased the visceral fat weight; different animal fatty oils i-crease in white blood cell count may improve rat body immunity. Different animal fatty oils had different i-mpact on plasma glucose and plasma lipids: ovine fatty oil raised HDL-C and TG based; swine fatty oil ra-ised HDL-C based; however bovine and equine fatty oils extremely increased total cholesterol based. Diff-erent animal fatty oils had no impact on LEP; ovine and swine fatty oils all elevated the melondialdehyde;bovine and equine fatty oils could significantly increase SOD levels in rats, suggesting the bovine and equi-ne fatty oils has antioxidant effect. The specific mechanisms of different animal fatty oils on physiologicaland biochemical and blood related factors in rats needs further study. This study provides support for theph-ysiological and biochemical experiments of the intuitive effect of ovine, swine, bovine, equine fatty oilsin rats. |
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