Effect Of Peptide And Cysteamine On Growth Performance And Mechanism In Weaned Pigs

This test is mainly designed to investigate the effects of feed peptide and cysteaminesupplements on performance, nutrient apparent digestibility and serum biochemicalparameters of weanling piglets. Ninety six28-days-old cross-bred (Doric×Landrace×Large White) weaned piglets were randomly allotted to A, B, C, D four treatment groupswith three replicates per treatment and eight pigs per pen (four gilts and four barrows) atsimilar initial body weight. Control group (A) was fed the basal diet supplemented withcolistin sulfate0.16‰+salinomycin0.04%; Group B with3%of small peptides,andnutrient level of Group B was the same to basal diet; Group C was fed basal diet＋120mg/kg cysteamine; Group D was supplemented with cysteamine120mg/kgon the basisof group B diets. The trial period is30days. Pig manure was collected for5days beforethe end of the trial, the blood was collected by anterior vena cava at the end of the trial.Results showed that the daily feed intake and daily gain were significantly improvedby C and D groups compared to conrol treatment (P<0.05), but not significant (P>0.05) tothe small peptide group (B group). Addition of120mg/kg cysteamine and3%smallpeptides and3%small peptides+120mg/kg cysteamine decreased feed/gain by2.89%,3.38%,4.83%separately (P>0.05). The addition of small peptides and cysteamineimproved the apparent digestibility of crude protein, crude fat, crude fiber, Ca, P indifferent degrees, but only the crude protein apparent digestibility increased significantly(P<0.05). Compared to control group, the serum protein levels of pigs fed with smallpeptides and cysteamine increased, but only the total protein level increased significantly(P<0.05). T3, T4, insulin, growth hormone level of B and C groups improved, but the SSlevel reduced (P>0.05). Addition of small peptides+cysteamine improved T3, T4, insulin,growth hormone levels significantly (P<0.05). In conclusion, compared to the antibioticgroup, the supplementation of small peptides and cysteamine significantly improve thegrowth performance of weaned piglets. Antibiotics can be replaced by small peptides andcysteamine. There are additive effects between small peptides and cysteamine. When thesmall peptides and cysteamine are added in the weaned pig diet at the same time, the besteffects are achieved.