| Objective:To explore the correlation the correlation between IL-2and liver function, hepatitis B virus (HBV) DNA in the patients with hepatitis C virus (HCV) infection by investigating statistical analysis of serum hepatitis B virus infection markers and liver function.Methods:The observation group contained600cases of patients with HBV infection from November2009to August2012in Yanbian Cancer Hospital and the control group also contained600cases of normal healthy individuals for body examination from the same period in the same hospital. ELISA was used for the detection of IL-2, real-time fluorescent quantitative polymerase chain reaction (FQ-PCR) for hepatitis B virus DNA and folly automatic biochemical analyzer for liver function index of the test.Results:The contents of ALT, AST, TBiL, DBiL and DNA values in the observation group were significantly higher than those in the control group(P<0.05). The expression of IL-2in observation group was significantly higher than that in the control group (P<0.05). The serum IL-2concentration in observation group was negatively correlated with HBV DNA values (P<0.05), and positively correlated with ALT and AST(P<0.05).Conclusion:IL-2is expressed with a higher level in sera of the HCV-infected patients. HCV can promote the secretion of IL-2, which is associated with liver function injury. The immune response mediated by IL-2can induce the body to clear HBV infection, but may increase the damage of liver cells. |
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