The Efficacy Analysis Of Laparoscopic Surgery For Early Stage Epithelial Ovarian Cancer

Objective To investigate the feasibility and safety of laparoscopy in surgical stagingof early-stage epithelial ovarian cancer. Methods The outcomes of55patients withearly-stage epithelial ovarian cancer who underwent laparoscopic (LPS group, n=29) orlaparotomy (LPT group, n=26) surgical staging at Xinjiang medical University ThirdHospital from March2007to February2010were retrospectively estimated. Theparameters including operation time, intraoperative blood loss, gastro intestinal recoverytime, postoperative complications, number of resected lymph nodes, and hospital staywere compared between the two groups. Results There were no between-groupdifferences in mean age, parity, body mass index, lymph nodes retrieved, or thepercentage of patients who were postmenopausal. Compared with LPT group, LPS grouphad significantly shorter operating time [(109.55±9.24)min vs (183.73±13.31)min,t=-4.703, P<0.001], less intraoperative blood loss [(59.66±8.43)mL vs (242.5±76.68)mL,t=-4.165, P<0.001）]and albumin reduction before and after surgery was significantlylower [(5.71±0.42)g/ml vs (10.67±0.55)g/ml,P＜0.001], less transfusion requirement[0(0/29) vs4(15.38%),P=0.044], faster return of bowel movement[(2.14±0.12)d vs(2.65±0.17)d,P=0.016]，less febrile[5(17.24%) vs12(46.15),P=0.021], less postoperativecomplications[1(3.48%) vs8(30.77%),P=0.010], There were no between-group significantdifferences was found in postoperative hospital stay, numbers of resected lymph nodes，recurrence or death rate（P＞0.05）. Laparoscopic group,3-year survival rate was89.66%,the laparotomy group to92.31%. Log-rank test results show that P>0.05. ConclusionsLaparoscopy and laparotomy had similar surgical staging feasibility and safety, whereaslaparoscopy shows more favorable operative outcomes. Laparoscopic surgical staging isfeasible and safe for early-stage epithelial ovarian cancer in a short term, and its long-term outcomes are to be further investigated.