Retrospective Analysis Of Different Surgical Approaches For Early Epithelial Ovarian Cancer

Objective: To follow up the clinical effects of different surgical approaches in the treatment of early epithelial ovarian cancer(e EOC)and explore the feasibility and safety of laparoscopic staging in e EOC.Methods: The clinical data 106 patients with e EOC who underwent laparoscopic(LPS group,n=34)or laparotomic surgical staging(LPT group,n=72)in Cangzhou Central Hospital from February 2012 to January 2020 were retrospectively analyzed.The intraoperative blood loss,the number of lymph nodes removed,postoperative complications,postoperative exhaust time,postoperative CA125 normal chemotherapy course(PNCC-CA125),initial relapse time,and death time were compared between the two groups.Results: The patients’ baseline characteristics were similar in both groups.Women in the LPS group had a significantly lower preoperative CA-125 value and smaller tumor volume(P<0.05).LPS group had less intraoperative blood loss(521.47±241.71)VS(790.83±385.56)ml,shorter gastrointestinal recovery time(2.00±0.60)VS(2.83±0.44)d and postoperative hospital stay(7.71±0.84)VS(8.56±1.29)d when compared with LPT group(P<0.05).No intraoperative complications occurred in both groups.The number of lymph node retrieved and postoperative complication rate,as well as the number of chemotherapy courses when CA125 decreased to normal and the postoperative pathological type,were similar in both groups(P>0.05).The recurrence rate(5.88%VS22.22%)in the LPS group was lower than that in the LPT group(P<0.05).The average follow-up time,mortality,relapse-free survival(RFS)and overall survival(OS)were similar in both groups(P>0.05).Conclusion: Laparoscopy surgical staging of early epithelial ovarian cancer has similar surgical and oncological outcomes to laparotomy,while laparoscopy has advantages of less trauma and faster recovery than open surgery,which is safe and feasible.