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The Expression Of GP73and AFP In The Tissue Of Early HCC And Its Significance

Posted on:2014-01-14Degree:MasterType:Thesis
Country:ChinaCandidate:Z L SiFull Text:PDF
GTID:2254330422964488Subject:Department of General Surgery
Abstract/Summary:PDF Full Text Request
Objective:To detect the expression of Golgiprotein73(GP73) and AFP in the tissue of earlyhepatocellular carcinoma(HCC), and investigate its significance.Methods:In this experiment, we have collected40cases of tumor tissue for early HCC and20cases of non-tumor liver tissue. Immunohistochemical staining was used to detect theexpression of GP73and AFP in the above-mentioned two groups of tissue.Results: In the early HCC tissues, GP73and AFP were expressed higher than that in thenon-tumor liver tissues, and GP73-positive expression was significantly higher than that ofAFP. And both there is statistical difference (p<0.05).Conclusions In the diagnosis of earlt HCC, GP73may be a more superior detectionindicator to AFP.
Keywords/Search Tags:GP73, Golgiprotein73, AFP, HCC, hepatocellular carcinoma
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