| Laryngopharyngeal reflux disease seriously affect the quality ofpeople’s lives. more and more attention,As social and economic progress.Patients with diverse clinical manifestations, the first symptom varied,often treatment in different Clinics，the incidence of LPRD still a lack ofcomprehensive and systematic study. LPRD is considered throatmanifestations of gastroesophageal reflux disease early, and found thatwith further research, LPRD was confirmed with GERD are two distinctdiseases. The LPRD the pathogenesis fully elucidated, possibly by morethan1or several factors acting simultaneously due, under certainphysiological and pathological conditions, abnormal changes in theorganizational structure of the gastroesophageal junction, USE tensionspontaneous decline orbecomes loose, regurgitation caused correspondingsymptoms was known as LPRD. LPRD be mainly for the throat symptoms,such as globus, frequent throat clearing, hoarseness, dysphonia, swallowingpoor, sputum，chronic cough,prolong the vocal warm-up time et al.and can cause nose, ear and lower respiratory tract symptoms, such as sinusitis,otitis media, such as asthma et. The lack of a unified LPRD diagnosticcriteria, diagnostic methods combined with a history、 signs and auxiliaryexamination. The double probe24h pH monitoring is considered the "goldstandard" diagnostic LPR, it can more accurately reflect the throat acidreflux. MII/pH value monitoring technology is relatively more objectiveand accurate. PPI experimental treatment in the primary hospital widelypopularized.The integrated treatment is accepted treatment principles，thatgeneral therapy combined with drug treatment, surgical treatment whennecessary. PPI is considered the treatment LPRD effective drugs.LPRDhas been recognized by the world as an independent disease， causing theworldwide research and concerns. However, the disease pathogenesis,diagnosis, treatment is still a lack of unified understanding, LPRDdiagnosis and treatment requires further clinical studies. |
PDF Full Text Request