The Correlation Of Age And HR-HPV Infections In Chongqing Cervical Cancer Patients

Objectives: to assess the prevalence of HPV(humanpapillomavirus)infections among the outpatients of a tertiary hospital basedon the distribution of age, providing the convincing evidence for theclinical application of HPV vaccine.Methods: a retrospective study was performed involving a sample of2480women. Cervical specimens were obtained for the detection ofHPV-DNA. The data of age and testing results were subjected to chi-squarestatistical analysis.Results: in this population,28.3%（703/2480）were positive forHPV-DNA detection, in which25.2%(624/2480)were HR-HPV（high-riskhuman papillomavirus） suffers. As to the subtype classifications,HPV-16(9.3%) was the most common HPV type, followed byHPV-52(3.3%).Most of HPV suffer（s85.6%） were single infections, whiledouble infections took priority of86.7%of the multiple. In cervical cancerpatients, HPV infections55.8%（106/188）were positive for HPV-DNAdetection, in which100%(106/106)were HR-HPV （high-risk humanpapillomavirus）suffers. As to the subtype classifications, HPV-16(19.15%)was the most common HPV type, followed by HPV-52(7.98%).Most of HPV suffers（96.2%） were single infections, The analysis on the basis ofage in Chongqing Women revealed that the distrubution of HPV infectionincreased while people get older. But the analysis in Chongqing cervicalcancer patients don’t show that.Conclusion: the subtype-specific and age-specific distribution of HPVinfection in Chongqing possesses an obvious heterogeneity, suggestingtheir necessary considerations in the application of HPV vaccines.