Systematic Review Of CPAP Therapy For Patients Of OSAHS After Stroke

Background: Many studies have shown post-stroke obstructive sleepapnea-hypopnea syndrome (OSAHS) can affect stroke short-term andlong-term prognosis, and continuous positive airway pressure (CPAP)treatment can reduce vascular inflammation and endothelial injury, thusreduce vascular complications and improve the prognosis.Objective: To evaluate the efficacy of CPAP for OSAHS patients afterstroke.Method: According to Cochrane systematic evaluation method,PubMed、CENTRAL (The Cochrane library)、Embase、 China AcademicJournal Full-text database、Chinese Biomedical Literature Database wereretrieved by computer to collect Randomized Controlled Trials(RCT).RESULTS: Of the four studies, two were high quality, the rest weremiddle quality. Results show that: the CPAP group compare to theconservative treatment group， the score of Canada scale、Montgomery-sberg Depression Rating Scale（MADRS） was statisticallysignificant.Rankin score、the Stanford Sleepiness Scale, Epworth SleepinessScale had improvement， SF-36score、 MMSE situation may have improvement, Barthel Index had little improvement.Conclusion: CPAP of OSAHA could improve sleepness、Depression、cognitive and movement after stroke。 With the low number of therandomized controlled trails, they can not fully reflect the efficacy. We needmore studies.