CN0Thyroid Papillary Carcinoma Metastasis Lymph Node In Central Line Risk Factors And Preventive Dissection Of Clinical Analysis Research

Objective: To explore factors influencing the metastasis of lymph node in Central Lineand preventive performed surgery complications and prognosis of lymph node in centralregion, clear clinical analysis negative (cN0) in thyroid papillary carcinoma lymph nodecleaning treatment of the clinical value of prophylactic Central Line group andfeasibility.Methods: Through systematical retrospective analysis of46cases with cN0papillarythyroid carcinoma of The Second Affiliated Hospital of Dalian Medical University fromNov2010to Mar2013. statistics on the size, age, gender, neoplasm invading thyroidcapsule, number of primary tumors, tumor location and tumor of single and double side,to explore its relationship with metastasis lymph node in central region, expoundscleaning the clinical significance of lymph node in central region, the statisticalincidence of complications and prognosis.Results:46patients in8cases of lymph node metastasis positive in central region, thetotal transfer rate was11.7%. Age and lymph node metastasis rate in central there wasno statistically significant difference between the two groups (X squared=0.89, P>0.89); Gender and lymph node metastasis rate in central there was no statisticallysignificant difference between the two groups (X squared=0.13, P>0.13); Tumor sizeand lymph node metastasis rate in central difference between the two groups wasstatistically significant (X squared=4.34, P <0.05). Capsular invasion and lymph nodemetastasis rate in central difference between the two groups was statistically significant(X squared=4.57, P <0.05); Number of tumors with lymph node metastasis rate incentral difference between the two groups was statistically significant (X squared=4.43,P <0.05); Tumors with lymph node metastasis rate in central there was no statisticallysignificant difference between the two groups (X squared=0.39, P>0.39); Tumors located in single and double side with lymph node metastasis rate in central there wasno statistically significant difference between the two groups (X squared=0.62, P>0.62); Positive transfer and tumor invasion and lymph node in central region capsule,tumor diameter greater than1.0cm, and the primary focal for multiple, related with age,gender, lesion area and whether in single and double side has nothing to do. Totalincidence of postoperative complications was13.0%(6/46), temporary parathyroidfunction decline the incidence was4.3%(2/46), returned to normal after treatment. Nopermanent laryngeal recurrent nerve and parathyroid damage and other permanentcomplications. Follow-up of1~26months,2patients were lost to follow-up, and no inpatients with distant metastasis, tumor local recurrence and death.Conclusion: Lymph node metastasis rate was higher in the center, this article is11.7%.Positive transfer and tumor invasion and lymph node in central region capsule, tumordiameter greater than1.0cm, and the primary focal for multiple, related with age,gender, lesion area and whether in single and double side has nothing to do. Aboutcleaning the Ⅵarea can prolong survival in patients with lymph node, the future needto large-scale randomized prospective research and long-term follow-up to verify thepositions. Although prophylactic Central Line lymph node cleaning effectiveness ofpostoperative complications will appear a certain proportion, but more for the temporary.Because the thyroid papillary carcinoma lymph node metastasis rate was higher in thecenter, so the implementation of this procedure has very important clinical significance;If the performer skilled operation, implementation of the operation is very safe.