Anti-asthma Soup Treating Bronchial Asthma With Heat Wheezing Curative Effect Observation

Research background:bronchial asthma is a common disease of respiratory system, composed of many cells and cellular components involved in chronic inflammatory airway diseases, clinical recurrent, associated with wheeze expiratory dyspnea as its basic feature, multi contact allergens in after the attack, increase. In the recent20years, the prevalence of bronchial asthma has been significantly increased, has become a global public health and social problem, according to the world health organization (WHO) global about300million asthma patients, the prevalence of1%to13%, the number more than30million asthma patients in our country, prevalence of about1%-4%, many patients course for more than ten years to decades. As domestic air quality serious decline, in the great cities of the Chinese people obviously improve the morbidity and mortality, the resulting medical costs increase the burden of families and social pressure, so want to be in the clinical research can be more effective method of treatment, control of bronchial asthma. In this paper, our hospital respiratory outpatient and ward treatment of60cases of bronchial asthma patients with chronic moderate (TCM Syndromes of asthma of heat type) paper summarizes the related information, from clinical symptoms improve TCM symptoms (total integral, single Chinese medicine symptom integral), pulmonary function and safety indicators evaluation set soup treating chronic asthma duration (asthma of heat type) of clinical efficacy and safety.Objective:a randomized controlled single blind method, clinical symptoms and were eligible for asthma asthma patients in clinical (including asthma, cough, sputum, throat wheezing and wheezing, tongue, pulse like), lung function (including FEV1, PEF) in the aspects of treatment before and after the change, as the study of Dingchuan Decoction on asthma chronic persistent period (moderate patients with asthma of heat type) influence and improve lung function in clinical manifestation, the system evaluation Dingchuan Decoction Treatment of chronic persistent asthma patients (moderate asthma of heat type) clinicalefficacy and safety.Methods:according to the design scheme of the inclusion and exclusion criteria for the selection of chronic persistent asthma patients (moderate asthma of heat type)60cases, the clinical trial design method of single blind randomized into Chinese medicine group (treatment group) and Western medicine group (control group), according to the design of1:1,30cases in each group. Among them, the control group in the average age35.4±1.31years, to the Shah Fluticasone Propionate/Salmeterol Xinafoate, montelukast, doxofylline treatment; the treatment group in the average age36±1.22years, treated with Chinese medicine of Dingchuan decoction combined with Shah Fluticasone Propionate/Salmeterol Xinafoate, montelukast, doxofylline treatment, treatment time of two groups for1months. After1months of clinical symptoms were observed in the two groups before and after treatment (including asthma, cough, sputum, throat wheezing and wheezing)(TCM symptoms integral, single symptom score), lung function (including FEV1, PEF) changes and the safety index. By statistical analysis, two groups of patients before and after treatment of illness and improve safety. Pulmonary function specific steps in strict accordance with our hospital Jaeger spirometry steps.Results:(1) compared the TCM syndrome total score:two groups of different P<0.05, the treatment group the total clinical control+markedly effective rate was90%,60%in the control group, the treatment group in treatment of asthma was better than control group.(2) single TCM Symptoms Score:two groups of dyspnea, cough, expectoration symptoms were between P<0.05, the treatment group before and after the treatment were better than those in the control group, the therapeutic effect of two groups of the throat, wheezing and wheezing and no difference in P>0.05, similar effect.(3) pulmonary function evaluation:the main index of the two groups of pulmonary function in patients with FEV1, PEF improvements, the differences between the two groups after the treatment to improve significantly, P value of <0.05, no significant difference between the two groups before and after treatment to improve the degree of improvement after the treatment in the two groups, there is no difference, P>0.05, curative effect two groups of FEV1, PEF similarity.(4) ADR monitoring: electrocardiogram and liver function of two groups were no obvious abnormality of blood.Conclusion:(1) the two group received the treatment according to the design scheme, the total effect of therapeutic effect in TCM syndrome integral, shape effect and improve lung function and good, although the effect of the two groups in the treatment of throat wheezing, wheezing and lung function was similar, but the treatment group points, dyspnea, cough, expectoration in improved total effect than the control group, results show that, Dingchuan Decoction in the treatment of bronchial asthma effect is good, especially in improving asthma, cough, expectoration symptoms, integral effect and drug combination is better than single western medicine;(2) patients in the two groups were no blood, ECG were obviously abnormal, with clinical safety better two regimens in the treatment of bronchial asthma. To sum up, can confirm Dingchuan Decoction in the treatment of bronchial asthma patients (chronic moderate asthma of heat type) has good curative effect, with a single western medicine or single with the clinical curative effect of traditional Chinese medicine and Western medicine combined treatment better, also have good security, worth in clinical application. Conclusion:heat asthma treatment is feasible from the gloomy, Dingchuan Decoction in treating asthma curative effect good.