Analysis Of Clinical Diagnosis And Treatment Of Pancreatic Cystic Neoplasm

Objective:To summary the experience of diagnosis and surgical treatment ofpancreatic cystic neoplasm, in order to provide reference for clinicaldiagnosis and treatment of the disease.Materials and Methods：This study were retrospectively analyzed the data of56patients withpancreatic cystic neoplasm in the department of hepatobiliary andpancreatic surgery in Jilin university Bethune first hospital from January12011to January12014，analysis the data of pancreatic cystic tumor inage, sex, tumor location, pathological results, imaging examination,operation mode and postoperative complications. To study thepreoperative tumor marker levels and postoperative pathological findingsof benign and malignant relationship, the incidence of postoperativecomplications of different operation.Results:1female patients with pancreatic cystic tumor accounted for69.6%,the average age is48.8years old, male patients accounted for30.4%, theaverage age is47.6years old. The location of the tumor located inpancreas body and tail (55.4%) and head (33.9%), those located in thepancreatic neck is smaller (10.7%).2. Among56cases of pancreatic cystic neoplasms, serous cystic neoplasm accounted for19.6%, mucinous cystic neoplasm accounted for39.3%, intraductal papillary mucinous neoplasm accounted for16.1%,solid pseudopapillary neoplasm accounted for25%. There was asignificant difference in gender distribution of various types of pancreaticcystic neoplasms.3. All of the22patients with mucinous cystic neoplasms underwenttumor marker examination. According to the pathological results thesecases were divided into the benign tumor group and malignant tumorgroup, CA-199value of two groups was respectively14.2±13.5ng/L(2.1-47.6ng/L) for benign and175.1±35.5ng/L (123.2-202.9ng/L)formalignant, there was a significant difference (P=0.007). CA-242value oftwo groups was respectively6.4±4.8ng/L (1.7-20.0ng/L)for benign and31±15.7ng/L (15.8-52.1ng/L)for malignant. Benign tumor group’sCA-242were lower than those of malignant tumor group, there was asignificant difference (P=0.021).4Major postoperative complication was pancreatic fistula andhemorrhage of digestive tract, the rates were respectively19.6%and1.8%,4patients with grade A pancreatic fistula,6cases of grade Bpancreatic fistula,1cases of grade C pancreatic fistula.Conclusions:Pancreatic cystic tumor often occurred in middle-aged women,common lesion part was pancreatic body, tail and the head. The most common pathology type was mucinous cystic tumor and there was asignificant difference in gender distribution of various types of pancreaticcystic neoplasms.. The diagnostic accuracy of conventional B ultrasound,CT, MRCP examination were high, Tumor marker examination resultsmay have some guiding significance for judgement on benign andmalignant tumor before operation. The disease operation resection ratewas high, pancreatic fistula was a common postoperative complications,the prognosis was good.