| Objective The study intends to detect Tei index measured by Tissue Doppler imaging (t-Tei), ventricular EF value and modified Tei index in normal adults using pulsed Doppler spectrum.①The present study aims to compare various indexes reflecting the cardiac function with age and determine which is more sensitive through dividing the normal population into groups and measuring their cardiac function;②To determine whether Tei index should be measured in the long axis transection of the left ventricle or the apical four-chamber transection;③To determine whether Tei index can correct the traditional left ventricular ejection fraction and make the left ventricular ejection fraction more sensitive and objective in evaluation of cardiac function.④There are few indexes currently in the measurement of right heart function for special right ventricular anatomy. The appearance of Tei index can fill the gaps in the measurement of right heart function, and has an important clinical significance. The present study aims to deduce a more accurate and sensitive ultrasound index for evaluation of cardiac function through the changes in the left and right ventricular function in normal population with age, and determine whether there is a feasible corre ction formula between this index and the traditional EF value and other indexes, in order to optimize various indexes.⑥The present study aims to research and find the basic regulation of changes in the left and ventricular compliance and texture with age with respect to the heart anatomy.Materials and Methods A total of three hundred patients underwent physical examination. They were all confirmed without cardiovascular disorders through medical history, physical examination, electrocardiography, and echocardiography. They were divided into eight groups by age.1.(From18to20years old)2.(From21to30years old)3.(From31to40years old)4.(From41to50years old)5.(From51to60years old)6.(From61to70years old)7.(From71to80years old)8.(Over80years old) The ultrasonography was performed using a digital color Doppler ultrasound diagnostic unit (α7whole-body color Doppler ultrasound, Aloka, Japan) and M3S probes (with the frequency from2.0MHz to4.0MHz). The patient was in the left lateral position, synchronously, ECG was displayed. The patient first underwent conventional echocardiography. Then the parasternal long axis transection of the left ventricle, aortic short axis transection, apical four-chamber transection, apical five-chamber transection, apical long axis transection of the left ventricle were taken respectively. Under the imaging condition of pulsed-wave Doppler (PWD), the sample volumes were placed in mitral valve orifice and aortic valve orifice, respectively. The flow spectrum was recorded. The measurement indexers in the echocardiography included①the left ventricular ejection fraction (LVEF) measured by Simpson method;②the left ventricular Tei index measured by pulsed Doppler;③the right ventricular Tei index measured by pulsed Doppler;④the modified Tei index in the isovolumetric contraction period of the left ventricle measured by pulsed Doppler;⑤the modified Tei index in the isovolumetric relaxation period of the left ventricle measured by pulsed Doppler. Each index was measured in three cardiac cycles and the average value was calculated.Results (1) The specific value of the modified Tei index were significantly different in the isovolumetric contraction period of the left ventricle in healthy adults among different age groups (P<0.05).(2) The specific value of the modified Tei index were significantly different in the isovolumetric relaxation period of the left ventricle in healthy adults among different age groups (P<0.05).Conclusion (1) The specific value of the modified Tei index was reduced in the isovolumetric contraction period of the left ventricle in healthy adults with age.(2) The specific value of the modified Tei index was increased in the isovolumetric relaxation period of the left ventricle in healthy adults with age. |
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