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Focus Dissection Of Lymph Node Clinico-Pathological And Prognosis Analysis In Thoracic Esophageal Carcinoma

Posted on:2015-02-23Degree:MasterType:Thesis
Country:ChinaCandidate:Y M ChenFull Text:PDF
GTID:2254330431952804Subject:Oncology
Abstract/Summary:PDF Full Text Request
[Objective] To investigate the strength of thoracic esophageal carcinoma lymph nodes metastasis, focus dissection of lymph nodes the clinicopathological features and prognostic analysis,provide a reference for surgical focus dissection of lymph node.[Methods] Selected515cases of thoracic esophageal carcinoma clinical data in patients with radical surgery, research subcarinal, paraesophageal, left gastric artery lymph node metastasis relationship with clinicopathological factors, the analysis focused on lymph node dissection group and no dissection group impact on postoperative complications and survival. Using SPSS16.0software package for clinicopathological factors in univariate analysis and multivariate Logistic regression, survival analysis was performed using the Kaplan-Meier method, using the Log-rank test comparison between their groups.[Results]515cases of thoracic esophageal carcinoma patients, subcarinal lymph node metastasis in61cases(14.5%), paraesophageal lymph node metastasis in91cases(23.7%), left gastric artery lymph node metastasis in97cases(31.4%). Univariate and multivariate analysis showed:subcarinal lymph node metastasis and tumor length, degree of differentiation and depth of invasion(P<0.05); paraesophageal lymph node metastasis and depth of rumor invasion(P<0.05); left gastric artery lymph node metastasis and tumor location tumor differentiation and depth of invasion(P<0.05). The group focused on cleaning lymph node dissection and postoperative complication incidence of dissection group had no significant relationship(P>0.05). Survival analysis showed:paraesophageal lymph node dissection group and no dissection group N1-3patients in1year,3years,5year survival rates were significantly different(P<0.05), left gastric artery dissection group and no dissection group NO, N1-3patients in1year,3year,5year survival rates were significantly different(P<0.05).[Conclusion] Thoracic esophageal carcinoma should be possible for the next higher transfer rates of the paraesophageal and left gastric artery lymph node dissection completely, including its surrounding adipose tissue. Esophageal lesions invading the full thickness or lesion length>3cm of the patients can be routinely implemented subcarinal lymph node dissection. In N1-3patients, paraesophageal and left gastric artery lymph node dissection can improve the survival rate.
Keywords/Search Tags:Esophageal cancer, lymphatic metastasis, complications, prognosis
PDF Full Text Request
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