| Objective:Make neurophysiological examination in premature ejaculation patients, analysis its change and clinical application value in patients with premature ejaculation such as penile sensory thresholds, somatosensory evoked potentials, bulbospongiosus reflex threshold.Method:30cases of patients with premature ejaculation are screened through history, physical examination, laboratory tests, and Chinese patients with premature ejaculation and other sexual function score.(1). According to CIPE-5score,30patients were divided into three groups, penile sensory thresholds, pudendal nerve somatosensory evoked potentials, bulbospongiosus reflex threshold were measured in the private and peaceful environment. Record inspection results and pairwise comparison;(2). According to the patient’s symptoms associated with premature ejaculation, the30patients were divided into merger ED group, the combined group and the combined prepuce prostatitis group; statistical analysis each set of data.Results:(1).30cases of premature ejaculation, penis biological sensory thresholds, the latency somatosensory evoked potentials, bulbospongiosus emission threshold, the incubation period was4.70±1.65mA,40±1.93ms,29.05±15.14mA,36.36±9.60ms. Which penis biological sensory thresholds, bulbospongiosus reflex threshold is lower than normal reference values (7.44±1.29mA,35.36±4.92mA), the difference was statistically significant (P<0.05), pudendal somatosensory evoked potentials and bulbospongiosus reflex latency and normal reference values (39.96±5.13ms,35.97±19.62ms) has no statistical significance (P>0.05).No significant correlation (P>0.05) between the30patients with positive test results of various size and age and disease duration. Only penile sensory thresholds, bulbospongiosus reflex threshold has a significant correlation (P<0.05) with CIPE-5score.(2). Penile sensory thresholds in patients with severe (3.48±0.91mA) and the other two groups (5.22±1.47mA,5.40±1.72mA) have significant difference between the compared (P<0.05); Bulbospongiosus reflex threshold was statistically significant (P <0.05) between patients with mild (38.3±16.47mA) and severe patients (22.82±8.68mA); Somatosensory evoked potential latencies and bulbospongiosus reflex latency in three groups have no statistical difference (P>0.05).3In the prepuce premature ejaculation combined with the control group, only penile sensory thresholds (3.13±0.68mA,5.61±1.32mA) were significantly different (P <0.05), while the three other non-significant difference (P>0.05).Premature ejaculation in the merger ED Group and non-ED group, the latency somatosensory evoked potentials (38.72±2.07ms,40.74±1.43ms) and bulbospongiosus reflex threshold (21.15±11.05mA,33.59±15.57mA) has statistically significant (P<0.05), bulbospongiosus reflex latency and penile sensory thresholds were no significant differences in the two groups (P>0.05).In premature ejaculation combined with prostatitis group, only bulbospongiosus reflex threshold (18.26±7.42mA,37.31±14.38mA) was significantly different (P<0.05), three other tests were not statistically different (P>0.05).Conclusion:(1) Penile sensory thresholds and bulbospongiosus reflex threshold detection can be used as an objective indicator of premature ejaculation.(2) In patients with severe CIPE-5score, the penile sensory thresholds and bulbospongiosus reflex threshold were significantly reduced, and therefore, these two indicators can be used as evaluation of treatment effect in patients with premature ejaculation.(3) In patients with redundant prepuce, and penis perception threshold was significantly reduced, suggesting that the lower sensory thresholds due to prepuce of the penis may be organic causes of premature ejaculation; In patients with ED’s, DNSEP latency and bulbospongiosus reflex thresholds were significantly lower, indicating that ED patients with neurological abnormalities can lead to premature ejaculation; In patients merge prostatitis, bulbospongiosus reflex threshold was significantly reduced, which may be caused by their symptoms of prostatitis and patients’anxiety of prostatitis. |
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