Analysis Of Efficacy Of Somatostatin In The Treatment Of Intestinal Obstruction

Objective To investigate clinical efficacy of somatostatin in postoperative adhesive intestinal obstruction.Methods The data of56patients with intestinal obstruction from Apr.2011to Dec.2012were analyzed by prospective study.All patients were randomly treatmented by traditional conservative therapy and plus somatostatin therapy. Experimental group (30patients) and control group(26patients). Patients in the control group were treated with traditional therapy including fast,effective gastrointestinal decompression, Chinese Medicine oral administration and retention enema intravenous,fluids to correct electrolyte imbalance,parenteral nutritional support,antibiotics and bowel lavage.Patients in the experimental group were treated with traditional therapy plus somatostatin therapy. Compare symptoms(the remission rate of abdominal pain and distention,anal exsufflation time),gastrointestinal decompression amount and time,average days of hospitalization, the rate of transfer surgical operation.Result Compared with the remission rate of abdominal pain and distention (73.07%)of the control group,the experimental group has better efficiency rate(93.33%)(P<0.05).The average time and amount of gastrointestinal decompression,average days of hospitalization, improvement of clinical symptoms and anal exsufflation time in the experimental group was lower than that in the the control group(P<0.05).The rate of transfer surgical operation in the control group was similar with the experimental group.Conclusion In traditional therapy plus somatostatin cure adhesive intestinal obstruction can significantly improve the abdominal pain and distention,cut down average time gastrointestinal decompression and days of hospitalization,ahead of anal exsufflation time,but the rate of transfer surgical operation did not be reduced.