Preparation Of Functional Hydroxylapatite Nanofiber Composites And Their Property

Hydroxylapatite [HA,Ca10(P04)6(OH)2] with good biocompatibility and bioactivity, is the main inorganic component of human bones and teeth, widely applied in the field of bone tissue engineering. In addition, hydroxyapatite has potential value in the field of adsorption because of its unique crystal structure. The aim of this paper is obtain HA functional composite nanofiber by combined ZnO or active carbon with HA via electrostatic spinning technique. The polyvinyl alcohol/hydroxyapatite/zinc acetate (PVA/HA/Zn(OAc)2) hybrid nanofibers membrane was used to prepare as a precursor of target material, and meso-HA/ZnO nanofibers were obtained via calcinations at 650℃for 2 h. Structure and morphology of nanofibers through a series of tests were characterized.Theantibacterial activities of meso-HA/ZnO nanofibers towards Staphylococcus aureus(S. aureus, ATCC6538) and Escherichia coli (E. coli,8099) were evaluated. The results showed a good antibacterial activity towards two kinds of bacteria.Meso-HA/ZnOcomposed ofhexagonal HA and hexagonalwurtzite ZnO, showed a wormhole-like shape. The specific surfacearea of meso-HA/ZnO nanofibers was determined to be 24.81 m2/g. And its pore sizes were mainly distributed around 25 nm.The inhibition efficiency of meso-HA/ZnO nanofibers increased with the increase of ZnO/HA ratio, however, S.aureus was more sensitive to meso-HA/ZnO nanofibers than E. coli. The meso-HA/ZnO nanofiberswith ZnO/HA ratio at 1:10 exhibited effective antibacterial activity towards S.aureus, whereas, the ZnO/HA ratio was raised up to 1:5 towards E.coli.The continuous and uniform PVA/HA/glucose nanofibers with the HA/Glucose ratio of 1:3 and 1:5 fiber presented asmooth surface and a diameter at 300 ± 10 nm and 250 ± 8 nm, respectively.The synthesis hydroxylapatite/activated carbon (HA/AC) nanofibers were obtain from PVA/HA/glucose nanofibers electrospun nanofibers by hydrothermal reaction at 180 ℃ for 16 h. The HA/AC nanofibers were composed of hexagonal HA andactivated carbon, HA gathered in between twocarbon ball. The specific surfacearea of meso-HA/ZnO nanofibers was determined to be 30.01 m2/g. And its pore sizes were mainly distributed around 29 nm. The adsorption activity of HA/AC nanofibers towards cobalt ions were evaluatedand discusses the influence of the ionic strength, pH and adsorbent concentration. The thermodynamic parameters implied that the sorption process is spontaneous and endothermic. Adsorption datas showed that the kinetic sorption of Co(Ⅱ) on sorbent agreed well with the pseudo-second-order model. The comparison of isotherm models illustrated that the Langmuir model described the equilibrium datas of Co(Ⅱ) ions sorption better than the Freundlich model.