Research On The Distribution And Removal Of Antibiotics In Different Water Bodies

Antibiotics is produced by organisms(including microbes, plants and animals) in their life activities, or by chemical synthesis, which can selectively inhibit other biological function under low concentrations. In recent years, the pollution of the ecological environment by antibiotics and potential threat to human health has attracted lots of attention, and antibiotic residues and pollution problems are keen to be solved.In order to understand the concentrations of antibiotics in different waterbodies, and its distribution over time and space, pretreatment of solid phase extraction(SPE) and high performance liquid chromatography tandem mass spectrometry(UPLC/MS/MS) detection method was adopted to measure concentrations of 9 kinds of typical antibiotic in three reservoirs in southern city and in Songhua river in Harbin at different time of a year.9 antibiotics in four types of antibiotics, including macrolides(erythromycin), quinolones(norfloxacin, ofloxacin, ciprofloxacin), tetracycline(oxytetracycline and chlortetracycline hydrochloride), sulfonamides(sulfamethoxazole, sulfadiazine) were measured. For the closure reservoir, 9 antibiotic concentration is higher in spring, and lower in summer and fall. The antibiotic concentrations near the bank were higher than the river center. Antibiotics concentration in A and B were lower than in the water source C. In terms of open source(i.e. the songhua river), concentrations of antibiotics were the highest during ice and snow melt period, and the surrounding environment highly affected the antibiotics levels.Antibiotics in two drinking water treatment plants(i.e. J and K) were measured. Antibiotics were barely removed(by 10%- 20%) in coagulation and precipitation. 10%- 40% antibiotics were removed in filtration. Terramycin and sulfadiazine can be removed more effectively(by 59% and 62% respectively) in V filter of J water plant. Total removal efficiency of these two plants towards 9 antibiotics was in the range of 40%- 50%.Pyridine type iron(a catalyst) was used in fenton-like oxidation for 9 antibiotics removal under different conditions. When the ratio of target: catalyst: oxidant was constant, 99.99% erythromycin can be removed; 50% sulfadiazine, chlortetracycline hydrochloride, and oxytetracycline were removed; 30% of the rest 5 antibiotics were removed under different conditions. The ozone oxidation removed more than 90% of 9 kinds of antibiotics. Over acid(pH = 4.3), over alkali(pH = 10.7) or dosage of ozone(too low <0.6 mg/L) negatively influenced the antibiotic removal.