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The Dynamic Surveillance Of Immune Antibody And Investigationthe Risk Factors On O Type FMD In Bovine In Altay Region From 2009 To 2014

Posted on:2017-05-30Degree:MasterType:Thesis
Country:ChinaCandidate:Y B HuangFull Text:PDF
GTID:2283330503989257Subject:The vet
Abstract/Summary:PDF Full Text Request
Foot-and-mouth Disease(FMD) is a highly contagious, acute and febrile disease caused by FMDV, which can be a long-range and rapid spread disease. Since FMD can cause huge economic losses and international influence, the World Organisation for Animal Health(OIE) ranked FMD the first one of all 15 A class diseases. And China also ranked FMD one of 14 first class animal diseases, which fully shows that governments’ concern of the FMD. Prevention and control of FMD is a serious and urgent problem that faced by all levels of government.The study determinated the immune antibody of O type FMD dynamically, investigated and analysed the risk factors for six years(2009-2014) in Altay region, research results are as follows:First, dynamic monitoring the immune antibody of Bovine type O FMD in Altay region.In order to find out the level and growth-and-decline law of Bovine type O FMD immune antibody in Altay region from 2009 to 2014, and discover and analyze the potential loopholes in vaccine immunization, LPB ELISA was used to monitor the antibody titer of 9022 FMD sera. From 2009 to 2014, the numbers of sample were 836, 1813, 1857, 1434, 1502 and 1580, respectively.Test results show that the six years from 2009 to 2014, altay region Bovine O qualification rate of FMD immune antibody(antibody titer 1:12 8 or higher) were 95.45%, 94.77%, 93.57%, 94.77%, 92.29%, 95.1%, 76.57%, 80.53%, 91.63%, 94.86%, 91.63%, the average immune antibody percent of pass is 91.34%.The highest was in the autumn of 2009(95.45%) and the lowest was in the autumn of 2012(76.57%). And scale farms were higher than scattering farm in macrocosm. The results suggested that the antibody of Bovine type O FMD in Altay region were kept at a high level from 2009-2014 which could better resist the invasion of FMD. To avoid the risk of inflection, monitor should be done before changing the vaccine.Second, investigation on the risk factors of Bovine type O FMD in Altay region.With the purpose of improving the level of prevention and control of FMD, ensuring the health of livestock in Altay region and safeguarding people’s health and social stability, this study adopted the advanced experience and practice of risk assessment system at home and abroad, combined with the situation in Altay. During February 2013 to February 2015, the FMD risk was assessed by date collection, interview and questionnaire survey in this region, choosing the epidemic history of FMD, circulation of livestock and livestock products, meteorological factors, the distribution of the surrounding wildlife, slaughter and processing factors, environment, livestock immune factors, feeding and management factors and 15 sub factors for reference. The results showed that 2014 Bovine type O FMD disease risk value of 0.3723-0.3723, the average risk value was 0.3924, each month for the whole year of Bovine type O FMD disease basic level in the medium level.The result shows that the Altay region has unique natural conditions and artificial barriers were established in National Road 216, 217 which could prevent the spread of the epidemic effectively. The whole prevention and control of FMD operated well. But there are high risk factors such as poor condition in small livestock trading market dynamics, health quarantine and disinfection and antibody-positive infected, etc., which need to be concerned and improved in the future.
Keywords/Search Tags:Altay region, Bovine, type O FMD, Immune antibody, Risk investigation
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