Refractory Idiopathic Thrombocytopenic Purpura Syndromes Distribution And Related Factors

PurposeIdiopathic thrombocytopenic purpura is a relatively common clinical hemorrhagic disease, its incidence is about one millionth chance, mostly female patients. Divided by acute onset cases, chronic idiopathic thrombocytopenia. Which has evolved in patients with chronic1/3into refractory idiopathic thrombocytopenic purpura. Western medicine for the treatment of ITP is currently widely used corticosteroid therapy for some patients with acute attacks, to the impact of gamma globulin therapy, to receive good results, when converted into refractory ITP ITP when the first-line treatment of ITP or second-line drugs, the effect is minimal, even if they can achieve a therapeutic effect, but also requires large doses and prolonged oral, but also easy to repeated attacks, platelets fluctuate significantly. Treatments can cause varying degrees of toxicity. In recent years, the advantages of Chinese medicine treatment RITP increasingly showing, despite remission from acute attack or medical terms, TCM treatment has drawbacks, but for control and maintain relatively high levels of platelet count, still has long-term significance. Can not cover its advantages, recent literature review shows that each hold their own individual physicians ideas and experiences in the treatment RITP have achieved good results. However at this stage the relationship of distribution and related factors RITP between TCM is still lack of guidance system specification. This article on a retrospective study of patients in our hospital for nearly10years50cases diagnosed RITP, statistical analysis of the relationship between TCM distribution and related factors in a rough understanding to our hospital for treatment RITP. MethodAll cases were from the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine Hematology ward, the total number of cases to50cases. Through the past10years, in line with our hospital diagnosis of refractory idiopathic thrombocytopenic purpura,50patients were analyzed retrospectively. Syndrome distribution observed in patients, age of onset, course of disease, clinical symptoms, when the number and efficacy of platelet-related hospitalization compared. Statistical analysis of the frequency of common clinical symptoms appear, describing tongue and pulse, the distribution of syndromes and syndromes associated factors. To understand the overall trend of RITP syndromes patients, as well as various syndromes treatment. Able to expect in clinical medicine treatment RITP overall grasp of the law.Results1, the proportion of male and female patients, female patients than male patients, covering a wide age range of patients, with a median age of onset is32years old, the sick sex ratio P>0.05, the relationship between the incidence of no correlation between gender2, RITP of TCM mainly Qi deficiency, blood stasis is the major syndromes, many of which syndromes and age there is no difference (P>0.05), while in the single deficiency syndromes in patients with non-yin patients between the ages between patients with syndromes no significant difference, there are obvious differences between patients with disease duration, the average duration was significantly greater than in patients with yin deficiency in patients with non-, indicating that the course does not exist yin deficiency or non-specificity of age, as well as progression, more patients will change for the deficiency syndromes; between the two cards in combination with non-blood stasis between QDBS course and age-related, found that the average duration and age of the patient’s basic QDBS the patients than in non-QDBS longer be large, can predict the outcome in line with traditional Chinese medicine and chronic illness and more virtual, chronic illness stasis theory, and with the progression of blood stasis syndrome type two card combination may become patients persistent syndromes, duration, and older patients are more prone to blood stasis symptoms.3, For RITP patients, former patients hospitalized platelets are below the basic20X109/L, and about80%of the patients had subcutaneous bleeding in some patients with oral mucosa and bleeding gums; minority patients have nasal bleeding, hematuria menorrhagia, etc. symptoms. Check against type and degree of bleeding-related statistics, we can see more patients and more severe the degree of bleeding syndromeConclusionRefractory idiopathic thrombocytopenic purpura TCM:mainly Qi deficiency and stasis, its single deficiency syndromes with mainly two card combination with blood stasis-based, multi-card portfolio basic to blood stasis and folders other syndromes based; the prevalence of male to female ratio showed no statistical difference; between single card type Age no significant differences between deficiency and non-deficiency patients, whereas the duration of deficiency The mean is greater than the non-deficiency patients, patients with presumed non-deficiency prolonged course deficiency may be converted into the patient. Two card combinations QDBS type and age of the patients was significantly greater than the average duration of the non-bl<ood stasis syndromes in patients (P<0.05); between the syndrome and the degree of correlation between bleeding:the more syndromes and folders more serious degree of bleeding...