| Objective:To learn the extent of surgical peritoneal cavity infections and provide the basis for the clinical use of antibiotics by testing the concentration of procalcition (PCT) and C-reactive protein (CRP) in the patients with peritoneal cavity infection.Methods:44patients were retrospectively analyzed who were hospitalized in integrated department, the second affiliated hospital of Kunming Medical University from June2011to June2012and they were divided into three groups including non-infected group, local peritoneal cavity infection and diffuse peritoneal cavity infection. There were8patients without peritoneal cavity infection including2cases of inguinal hernia, gallbladder polyps in3cases,3cases of gallstones in non-infected group,21patients with localized peritoneal cavity infection including21cases of acute suppurative appendicitis in localized peritoneal cavity infection group and15patients with diffuse peritoneal cavity infection including5cases of acute pancreatitis,5cases of gastric perforation,3cases of intestinal rupture,1case of gallbladder perforation,1case of acute gangrenous appendicitis with perforation.39cases of all had been confirmed by operation and5by iconography. Body temperature, leukocyte (WBC), neutrophil, CRP and PCT were tested while being hospitalized and the use time of antibiotic was calculated during hospitalization.Result:All those patience has been cured without death cases. Temperature, WBC, neutrophil percentage and CRP significantly increased in local peritoneal cavity infection group and disseminated peritoneal cavity infection group compared with non-infection group (P<0.05), but there was no statistical significance between local peritoneal cavity infection group and disseminated peritoneal cavity infection group (P>0.05). PCT significantly increased in disseminated peritoneal cavity infection group compared with non-infection group and local peritoneal cavity infection group (P<0.05) but there was statistical significance between local peritoneal cavity infection group and non-infection group (P>0.05). Simultaneously, the use time of antibiotic significantly extended in disseminated peritoneal cavity infection group compared with local peritoneal cavity infection group (P<0.05).Conclusion:1) CRP can determine whether there is a surgical peritoneal cavity infections (including local peritoneal cavity infection and diffuse peritoneal cavity infection), but can’t distinguish diffuse peritoneal cavity infection or local peritoneal cavity infections.2) PCT can distinguish difluse peritoneal cavity infection or local peritoneal cavity infections, but can’t distinguish local peritoneal cavity infection and non-peritoneal infections.3) The combination test of PCT and CRP can help to distinguish the non-infection of peritoneal cavity, local infection of surgical peritoneal cavity and the disseminated infection of surgical peritoneal cavity.4) The combination test of PCT and CRP has a certain guiding role of whether to use antibiotics. |
