Clinical Research On Strengthening Spleen And Reducing Phlegm Combined With Reinforcing Kidney And Regulating Menstrual Cycle In Treating Obese Women With Polycystic Ovary Syndrome

Purpose:This study is about the clinical effect of the treatment for obese women with polycystic ovary syndrome, deficiency of the spleen and phlegm. Through compared by observed before and after treatment in patients with clinical symptoms, hormone levels, insulin resistance index, body mass index, ovarian volume and other indicators, we can know the clinical effect about the treatment of strengthening spleen and reducing phlegm, combining with reinforcing kidney and regulating menstrual cycle.Method:This study collects60obese patients with polycystic ovary syndrome, and respectively divides them into the treatment group, who were treated with strengthening spleen and reducing phlegm, combining with reinforcing kidney and regulating menstrual cycle, and the control group, treated with strengthening spleen and reducing phlegm. Three months are a course of treatment. Through compared by observed before and after treatment in patients with traditional Chinese medicine symptom, menstrual cycle, body mass index, hormone levels, insulin resistance index, body mass index, ovarian volume and other indicators, we can know the two groups’ different clinical effect.Results:1、Change of TCM syndromes:After treatment, the TCM syndromes score and the menstrual cycle of two groups were significantly decreased (P<0.01). The effect of shortening the inter-menstrual period of two groups was significant (P<0.01), and the treatment group has a higher response rate on shortened inter-menstrual period than the treatment group (P<0.05). About the total effective rate on the TCM syndromes, the treatment group was83.33%, while the control group was76.67%. The treatment group’s clinical effect on the TCM syndromes was rather than the control group (P<0.05).2、Change of hormone levels:After treatment, serum LH, LH/FSH, T levels of the two groups were significantly decreased (P＜0.01). About the function of decreasing LH and T, The treatment group can do more than the control group (P＜0.05), and the degree of decline in LH/FSH was significantly better than the control group (P<0.01).3、Improvement of insulin resistance:After treatment, serum FINS, FPG, HOMA-IR levels of the two groups were significantly decreased (P<0.01). About the function of decreasing FPQ The treatment group can do more than the control group (P<0.05), and the degree of decline in FINS and HOMA-IR was significantly better than the control group (P＜0.01).4、Change of BMI:After treatment, BMI of two groups were significantly decreased (P＜0.01). About the function of decreasing BMI, the treatment group can do more than the control group (P＜0.05).5、Change of ovarian volume:After treatment, the ovarian volume of two groups patients in the treatment were significantly decreased|(P<0.01). About the function of decreasing ovarian volume, the treatment group can do more than the control group (P<0.05).6、General clinic effect:In the treatment group, the cure rate was10.00%, and markedly effective rate was46.67%, and effective rate was23.33%, while total effective rate was80.00%. In the control group, the cure rate was3.33%, and markedly effective rate was20.00%, and effective rate was50.00%, while total effective rate was73.33%. The general clinic effect of the treatment group was better than the control group (P＜0.05).7、Safety observation:During the test, the two groups of patients were not found in three general examinations abnormalities, liver and kidney dysfunction and significant adverse reactions during the test.Conclusion:The treatment of strengthening spleen and reducing phlegm, combining with reinforcing kidney and regulating menstrual cycle is effective for obese women with polycystic ovary syndrome, deficiency of the spleen and phlegm. It can Improve clinical symptoms, shorten inter-menstrual period, decrease serum LH and T levels, Improve insulin resistance, decrease BMI, decrease ovarian volume. In the same time, it is a safe treatment.