Electric Acupuncture And Warm Acupuncture On Kidney Marrow Deficient Type Of Knee Osteoarthritis Clinical Curative Effect And The Influence Of Serum Levels Of Cytokines

Objective:To compare the WOMAC symptom integrates、pain index、serious condition index and IL-1、TGF-β in blood by electro-acupuncture and warm-needling before and after treatment on knee osteoarthritis with deficiency of kidney and marrow. Then to confirm the therapy effect of electro-acupuncture and warm-needling on treating knee osteoarthritis with deficiency of kidney and marrow and to discuss the mechanism of the two ways on osteoarthritis.Methods:80patients were divided into electro-acupuncture group and warm-needling group randomly, and both with the treating principle "tonify the liver and kidney and warm the kidney and marrow". Acupoint selection combine local and discriminate together, main points: Neixiyan(EX-LE4)、Waixiyan(EX-LE5)、Xuehai(SP10)、Shenshu(BL23),matching points: Zusanli(ST36)、Yanglingquan(GB34)、Yinlingquan(SP9)、Ashixue. Add electro-acupuncture at the points nearby the knee-joint as Neixiyan、Waixiyan、Xuehai、Zusanli and use continuous wave with3-5HZ frequency and moderate stimulation for30min; warm-needling group use moxa on above points. Make the patients with local warm feeling without burning sensation was preferred. One time need10min and then for the second time with totally3times and end after the third time. Once two days,20days for a period and totally2months. And give grades of WOMAC symptom integrates、pain index、serious condition index and IL-1、TGF-β in blood before and after treatment and then do statistical analysis.Results:1. WOMAC symptom integrate:electro-acupuncture and warm-needling can both improve the WOMAC symptom integrate and particular emphasis on the three aspects. Electro-acupuncture is better than warm-needling on improving pain and daily function (P<0.05); and warm-needling on improving morning stiffness is better (P<0.05)2. Pain index:both the two groups can release the pain of osteoarthritis patients, but electro-acupuncture is overmatch (P<0.05)3. Serious condition index:the two ways can both improve the illness condition and electro-acupuncture is overmatch (P<0.05)4. IL-1and TGF-β:both groups can obviously reduce the content of IL-1in patients blood (P<0.05) and electro-acupuncture is better than warm-needling (P<0.05) and TGF-β content both obviously increased (P<0.05) and warm-needling is better (P<0.05)5. Overall efficacy:the clinical markedly effective rate of electro-acupuncture is57.5%, and the total effective rate is87.5%. But the warm-needling is37.5%, and it’s total effective rate is80%. Compared to the total effective rate between the difference (P>0.05), no statistical significance, but on clinical markedly effective rate in the treatment of patients with temperature the electro-acupuncture is better than the warm-needling (P<0.05).Conclusions:1. Electro-acupuncture and warm-needling can effectively release the clinical symptoms of knee osteoarthritis patients and improve the living quality; electro-acupuncture emphasis on analgesic effect and warm-needling preferred relieve articular morning stiffness.2. Electro-acupuncture and warm-needling can both effectively lower the content of IL-1and meanwhile add TGF-P content, and electro-acupuncture emphasis on IL-1and warm-needling on TGF-β...