The Correlation Analysis Between Epicardial Adipose Tissue Thickness, Body Mass Index And Coronary Heart Disease

Objective:This study was undertaken to investigate the relationship between epicardial adipose tissue thickness, body mass index (BMI) and coronary heart disease(CHD). The results of the study may provide new clinical reference index for prevention, prediction, treatment and rehabilitation of coronary heart disease.Methods:170patients with coronary heart disease and89control patients were included in the final analysis. Possible risk factors of coronary heart disease were screened by univariate and multivariate Logistic regression analysis. ROC curves analysis was applied to adjudge the predictive value of risk factor gotten from Logistic regression analysis for coronary heart disease diagnosis. Evaluate the relationship between related risk factors and the severity of coronary artery disease by multiple linear regression analysis based on Gensini score and related risk factors. CHD group, according to the BMI of overweight and non-overweight, compare the differences in risk factors between the two groups.Results:General data analysis showed that,in coronary heart disease group the age, smoking, high blood pressure, triglyceride (TG), epicardial adipose tissue thickness, prehepatic fat thickness was significantly higher than non-CHD group (P<0.05). By univariate and multivariate Logistic regression analysis showed that hypertension, epicardial adipose tissue thickness, prehepatic fat thickness to the existence of coronary heart disease have a significant impact (P<0.05). ROC curves analysis showed that epicardial adipose tissue thickness has a certain accuracy in predicting coronary artery disease, the best cut off point was4.25mm. epicardial adipose tissue thickness,and prehepatic fat thickness were positively correlated with Gensini score (P<0.05). CHD group, BMI and prehepatic fat thickness are relevant (P<0.05), and BMI is no significant correlation with epicardial adipose tissue thickness and Gensini score.Conclusion:Epicardial fat and coronary heart disease is closely related, is a risk factor for coronary heart disease. Epicardial adipose tissue has some predictive value for coronary heart disease. Epicardial adipose tissue and coronary artery disease severity was high positive correlation. In early prevention of non-coronary heart disease patients,weight management and rehabilitation guidance of patients with coronary artery disease, for the purpose of develop a guidance target,BMI combine with epicardial adipose tissue is better than BMI alone.