Clinical Observation Of Warming And Tonifying The Spleen And Kidney Combined With Moxibustion In Treating Ulcerative Colitis Of Spleen Kidney Yang Deficiency

Objective To observe the clinical curative effect of warming and tonifying the spleen and kidney yang deficiency of spleen and kidney combined with moxibustion for treatment of Ulcerative Colitis, and explore the possible mechanism of action.Methods Using random, control observation method,50cases of Ulcerative Colitis of spleen kidney yang deficiency patients were divided into two groups, namely treatment group and the control group. The treatment group (25cases) treated with oral administration of traditional Chinese medicine combined with moxibustion therapy, the control group (25cases) received oral sulfasalazine (SASP) treatment. Continuous observation of8weeks, changes in the total effect of the two groups, the main clinical symptoms were observed after treatment, make curative effect evaluation and evaluation of adverse reactions, and were followed up for6months to study the long-term effect.Results After treatment, the control of symptom score, Sutherland score is better than SASP group.Part of the symptoms disappear rate, the comprehensive curative effect, TCM syndrome curative effect was better than the control group (P<0.05). Two groups of mucosal healing rates were (32%vs20%), no significant difference (P>0.05). Two patients were followed up for6months, the recurrence rate was (8.33%vs41.18%), there was significant difference (P<0.05), has better long-term effects of the treatment group. No serious adverse events occurred in two groups.Conclusion Warming and tonifying the spleen and kidney combined with moxibustion for treatment of patients with spleen kidney yang deficiency type UC positive, can significantly improve the symptoms of patients, no significant adverse reactions, drug safety.