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Clinical Analysis On The Multiple Factors Of Fertility Preserving Surgery In Women With Early Stage Cervical Cancer

Posted on:2015-04-23Degree:MasterType:Thesis
Country:ChinaCandidate:F K LinFull Text:PDF
GTID:2284330452467041Subject:Obstetrics and gynecology
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Objective The aim of this article is to investigate the relative factors offertility preserving surgery in women with early stage cervical cancer.Methods133cases who have been performed surgery with I stage were studied usingretrospective analysis. Main relative factors include parametrial involvement,lymphovascular space invasion, lymph node metastases, ratio of invasion depth,tumor size, histological grade and clinical stage.Results①There was no parametrial involvements, lymphovascular spaceinvasions in women with Ia1stage.②There was no lymphovascular space invasionsand lymph node metastases in women with Ia2stage.③In88women with Ib1stage,there was10parametrial involvements (11.4%),19lymphovascular space invasions(21.6%),11lymph node metastases (12.5%).④In12women with Ib2stage, therewas1parametrial involvement (8.3%),2lymphovascular space invasions (16.7%),1lymph node metastases (8.3%).⑤The rate of metastases is higher in women whoseratio of invasion depth is more than1/2.⑥The rate of parametrial involvementsand lymph node metastases are higher in women whose ratio of invasion depth ismore than2/3.⑦Ratio of invasion depth does not related with lymphovascularspace invasions. Tumor size does not related to metastases.Conclusion In patients with Ia1stage, when there is no lymphovascular spaceinvasion, a fertility preserving surgery with cervical conization is suggested.When there is lymphovascular space invasion in women with Ia1stage, afertility-sparing surgery consisting of radical trachelectomy with pelviclymphadenectomy is considerable. In patients with Ia2stage, when there is nolymphovascular space invasion, a fertility preserving surgery consisting of radical trachelectomy with pelvic lymphadenectomy is suggested. As to women withIb1stage, when there is no lymphovascular space invasion, the ratio of invasiondepth is less than1/2as well as the tumor size is less than2cm, radicaltrachelectomy with laparoscopic pelvic lymph node dissection is feasible.
Keywords/Search Tags:Preserving
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