| Background and Objective :Acute myocardial infarction(AMI) has become an important reason for death in patients with coronary heart disease. Pump failure is one of major complication in acute myocardial infarction. Under the conventional treatment, the hospital mortality rates as high as 80% to 90%. Even by percutaneous coronary intervention(PCI) treatment, the patient’s mortality rate is still high. Intra-aortic balloon pump(IABP) can relieve left ventricular afterload, increase the blood perfusion of coronary artery, improve myocardial blood flow and cardiac function. The purpose of this study is to observe the treatment effects of IABP using in patients with AMI complicated with pump failure Methods:Retrospective analysis of 82 patients with AMI complicated with pump failure, they had in the First Affiliated Hospital of Zhengzhou University heart medicine for treatment in January 2012 to May 2014. They were divided into two groups: observation group implanted with IABP before emergency PCI, the control group did not implant IABP. Observe two groups in the hemodynamics, the BNP, echocardiography, length of hospital stay, follow-up of 90 days of survival rate and complication and so on whether there is a difference. Results:1. Observation group after treatment, the systolic pressure and diastolic pressure is significantly higher than the control group(88.4±12.5/60.0±10.5mm Hg vs 80.3±16.2/55.4±10.2mm Hg, P<0.05), That heart rate is significantly lower than the control group(80.5±18.5bpm vs 92.4±26.1bpm, P<0.05), That urine volume is significantly more than the control group(40.3±9.4ml/h vs 30.2±8.3ml/h, P<0.05), the differences were statistically significant(P<0.05).2. The BNP of observation group in 7 and 9 days after admission was significantly lower than the control group(692.95±151.79,591.23±190.03pg/ml vs 813.85±15.61,721.02±173.52pg/ml, P<0.05). The differences was statistically significant between them(P<0.05).3. The LVEDD of observation group in 7 days after admission compared with the control group have no significantly difference(49.81±2.23 mm vs 50.93±2.87 mm, P>0.05). The LVEDD of observation group in the 90 days after admission was significantly lower than the control group(56.12±2.39 mm vs 59.41±2.57 mm, P<0.05). The differences was statistically significant between them(P<0.05).4. The LVEF of observation group in 7 days and 90 days after admission was no significant difference compared with the control group(43.79±1.90, 40.74±3.67 vs 42.89±2.91,39.72±2.76, P>0.05).5. The survival rate in the follow-up of 90 days of observation group is significantly higher than the control group(90.5% vs 85.0%, P<0.05). The length of hospital stay of observation group was significantly shorter than the control group(13.5±4.2h vs 18.4±6.2h, P<0.05). The differences was statistically significant between them(P<0.05). Conclusion:1. IABP improved myocardial oxygen supply and peripheral tissue perfusion, and effectively improve the hemodynamics in patients with AMI complicated with pump failure.2. IABP can further reduce the BNP in patients with AMI complicated with pump failure, improve heart function and inhibiting left ventricular remodeling.3. IABP can significantly improve hemodynamics, rescue myocardial damage, so as to improve the long-term survival of patients. |
PDF Full Text Request